DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31871 and Lipm

DIOPT Version :9

Sequence 1:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_076392.1	Gene:	Lipm / 78753	MGIID:	1926003	Length:	422	Species:	Mus musculus

Alignment Length:	394	Identity:	143/394 - (36%)
Similarity:	228/394 - (57%)	Gaps:	29/394 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 RNLKSDVL------EDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIP-------KKGAQP- 115
            ||:.|..|      .:|.:...::|:..|||||.:.|.|:|||||.::|||       |:|::|
Mouse    29 RNVNSGHLPTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPV 93

  Fly   116 VLLMHGILDTSATWVLMGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHE 180
            |||.||:|..::.|:...|.:.||::|:|.|:||||||||||.:|:.|.:|:.|..|||.|::.|
Mouse    94 VLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDE 158

  Fly   181 MGKYDLPANIDYILSKTGYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKS 245
            |.::||||.|::||.|||.::|:|:|:||||.:.::..|..|....||....||||||.:...:|
Mouse   159 MARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKYARS 223

  Fly   246 PLFRTLVLFLDFLTAATRMLRI----TEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYN 306
            |..:       ||.....|:::    .||:..|:|.......:|....:.| :||||:.|:.|:|
Mouse   224 PGTK-------FLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQ-ICSNIILLLGGFN 280

  Fly   307 SEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFRKFDRG-YLRNQLEYNRMTPPDYDLSRV 370
            :..:|.:...|.::|||:|.|::.:.|:.|.:.||..|.||.| ..:||.:.|:.||..|.:..:
Mouse   281 TNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDM 345

  Fly   371 KVPVALYYSVNDLLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVR 435
            .||.|::....|.|.:...|..|..|:.|:|....:|  .:.|:||:|.:|....|||.::..::
Mouse   346 MVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIP--EWAHVDFIWGLDAPQRVYNEIIHLMK 408

  Fly   436 RVEN 439
            :..|
Mouse   409 QEPN 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	26/61 (43%)
		MhpC	93..436	CDD:223669	131/355 (37%)
		Abhydrolase_5	115..281	CDD:289465	70/170 (41%)
Lipm	NP_076392.1	PLN02872	50..408	CDD:215470	137/367 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831839
Domainoid	1	1.000	227	1.000	Domainoid score	I2491
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H28267
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8736
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1506
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840