DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31871 and lipa

DIOPT Version :9

Sequence 1:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	152/413 - (36%)
Similarity:	240/413 - (58%)	Gaps:	20/413 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SPFSYSSLSFKNLLNSVLLSSN-PNLAGGGRNLKSDVL----EDASLITPKLIRKYGYPSETHTV 95
            ||..:..::...|:.:|.|:.: |:....|  :..|:|    .:|::...:|||..|||||.:.|
Frog     3 SPTMWLLVAVTALIPAVALTDDVPSRIRHG--VAGDLLYSADPEATMNISELIRYRGYPSEEYEV 65

  Fly    96 VTKDGYILEMHRIP------KKGAQPVL-LMHGILDTSATWVLMGPKSGLGYMLSDLGYDVWMGN 153
            :|:|||||.::|||      .:|.:||: |.||:|...:.||.....:.||::|:|.|||||:||
Frog    66 LTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGN 130

  Fly   154 SRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILSKTGYEQVHYIGHSQGTAIFWVLC 218
            ||||.:|:.|.||:.|.:|||.|::.|:.|.||||.:|:|..|||.||:.|:||||||.|.::..
Frog   131 SRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAF 195

  Fly   219 SEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFLDFLTAATRMLRITEFMPNTKFLVDHSQV 283
            |..|...:||.....|||:|.:...||||.:..|| .:||  ...:....||:|.|..:...:..
Frog   196 SSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVL-PEFL--IEELFGKGEFLPQTYLITWLATH 257

  Fly   284 VCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFRKFDR 348
            .| .:|:..::|.||.||::|:|.:.||.:.:.|..||.|:|.|::.:.|:.|.::||..:.||.
Frog   258 FC-THAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDF 321

  Fly   349 GYLRNQLEYNRMTPPDYDLSRVKVPVALYYSVNDLLVSTTGVDRLARELPNVIDKYLVPMERFNH 413
            |...|.:.||:.|||.|.:..:.||.||:...||.|.....|..|..::.|::  |...:..:.|
Frog   322 GTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQVSNLV--YHKEIPDWEH 384

  Fly   414 LDFLWAIDVKPLVYNRLVRNVRR 436
            |||:|.:|....:||.::..:::
Frog   385 LDFIWGLDAPERMYNEIIAMMKK 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	27/60 (45%)
		MhpC	93..436	CDD:223669	134/349 (38%)
		Abhydrolase_5	115..281	CDD:289465	73/166 (44%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	27/60 (45%)
		PLN02872	50..409	CDD:215470	142/364 (39%)
		Abhydrolase_5	91..>229	CDD:289465	65/137 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I2528
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2899
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm47739
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080