DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31871 and lipf

DIOPT Version :9

Sequence 1:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_998569.1	Gene:	lipf / 406713	ZFINID:	ZDB-GENE-040426-2737	Length:	396	Species:	Danio rerio

Alignment Length:	403	Identity:	140/403 - (34%)
Similarity:	223/403 - (55%)	Gaps:	23/403 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LLNSVLLSSN----PNLAGGGRNLKSDVLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRI 108
            :|:.|:|:|.    ...|..|..|..:|..:.|    ::||.:|||:|...|||:|||||.::||
Zfish     5 VLSLVILTSGLVQYGQSALDGTGLDPEVNMNIS----EIIRHWGYPAEEFEVVTEDGYILSINRI 65

  Fly   109 P------KKGAQPVL-LMHGILDTSATWVLMGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSL 166
            |      .:..:||: |.||:|...:.||...|.:.||::|:|.|:|||:||||||.:|..|.||
Zfish    66 PHGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSCKHVSL 130

  Fly   167 NSDYQEFWDFTFHEMGKYDLPANIDYILSKTGYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSM 231
            :...:|:|.|:..||.|.||||.|::|...||.||:.|:||||||.|.::..|..|....||...
Zfish   131 DPRQKEYWKFSHDEMAKKDLPAVINFITKMTGQEQIFYVGHSQGTTIAFMAFSTMPELASKIKMF 195

  Fly   232 HALAPIAYIHDMKSPLFRTLVLFLDFLTAATRMLRITEFMPNTKFLVDHSQVVCHDNAMTQDVCS 296
            .||||:|.:...|||:.: |.:..:||  ...:....:|.|..:.:...:...|....::. :|.
Zfish   196 FALAPVATVGMTKSPMTK-LSVIPEFL--IWDLFGQKDFFPQNELIKFFATEFCSRKPLSV-LCG 256

  Fly   297 NILFLVAGYNSEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFRKFDRGYLRNQLEYNRMT 361
            |:.||:.|::.:.||.:..||..:|.|:|.|::.:.|:.|.:||.....:|.|...|...||:.|
Zfish   257 NVFFLLCGFDEKNLNMSRTPVYTAHCPAGTSVQNMIHWAQAVKSSKLMAYDYGRAGNMAHYNQST 321

  Fly   362 PPDYDLSRVKVPVALYYSVNDLLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLV 426
            ||.|::..:.||.|::....|.|.....|..|..::|.::  |...::.:.||||:|.:|....:
Zfish   322 PPLYNIQDMMVPTAVWSGGQDTLADPKDVALLLTQIPKLV--YKRDIKHWEHLDFIWGMDAPQEM 384

  Fly   427 YNRLVRNVRRVEN 439
            |.:::..:|  ||
Zfish   385 YEKMIEIMR--EN 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	25/60 (42%)
		MhpC	93..436	CDD:223669	122/349 (35%)
		Abhydrolase_5	115..281	CDD:289465	68/166 (41%)
lipf	NP_998569.1	PLN02872	4..393	CDD:215470	137/397 (35%)
		Abhydro_lipase	36..97	CDD:282003	26/64 (41%)
		Abhydrolase_5	78..242	CDD:289465	68/166 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574743
Domainoid	1	1.000	205	1.000	Domainoid score	I2877
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I3034
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm26515
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810