DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31871 and SPCC1672.09

DIOPT Version :9

Sequence 1:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_587880.1	Gene:	SPCC1672.09 / 2539344	PomBaseID:	SPCC1672.09	Length:	467	Species:	Schizosaccharomyces pombe

Alignment Length:	450	Identity:	136/450 - (30%)
Similarity:	214/450 - (47%)	Gaps:	64/450 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLHCLVALEVCGRAGAFTLLSPFSYSSLSFKNLLNSVLLSSNPNLAGGGRNL-KSDVLEDASLIT 79
            ||.|| |..:....|.|       |.|:    :.|.:...|.........:| ::..:.||:.|.
pombe    30 LLSCL-AFMIHNTLGLF-------YRSV----VRNEIKKRSKKRSRSRSVSLQRAKAIHDAADIR 82

  Fly    80 PKLIRKYGYPSETHTVVTKDGYILEMHRI------------PKKGAQPVLLM-HGILDTSATWVL 131
             ::.:..||..|.|.|.|:|.|||.:|||            |||  .||:.. ||:|..|..||.
pombe    83 -EMCKISGYYVEDHLVRTEDDYILCIHRISKDSPGRIGSPHPKK--LPVVYCHHGLLMNSEVWVC 144

  Fly   132 -MGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILS 195
             :.|::.|.:.|.:.|||||:||:|||:||:.|...:|..:|||||:..:..:||:|..|||||.
pombe   145 NVDPRNCLVFDLVNKGYDVWLGNNRGNKYSRQHLRFDSTDKEFWDFSIDDFAQYDIPDTIDYILK 209

  Fly   196 KTGYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAY---IHDMKSPLF---RTLVLF 254
            .:|..::.|||.|||||..:...|..|....||.|:.||||...   :|:.....|   |..:||
pombe   210 TSGQTKLTYIGFSQGTAQAFASLSIHPLLNDKINSLIALAPAISPKGLHNRVVDAFVKARPSILF 274

  Fly   255 LDFLTAATRMLRITEFMPN---TKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLP 316
              ||.....:|....|..:   .||.   ..|:.:        |.:.||   .::.:.::.....
pombe   275 --FLFGRKSILPSAGFWQSFLAPKFF---DAVLAY--------CLSQLF---NWSCQNISSYQRL 323

  Fly   317 VMLSHTPSGASIKQLEHFGQLMKSGHFRKFDRGYLRNQ--LEYNRMTPPDYDLSRVKVPVALYYS 379
            |..:|..|..|:|.|.|:.|:|:|..||.:|...|.:.  |:|.:..  .:..:.::.|:.|.:.
pombe   324 VSFAHLYSYTSVKCLVHWFQIMRSAEFRMYDNDQLGHDYFLKYYKAA--KFPTNNIRTPIYLIWG 386

  Fly   380 VNDLLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVRRVEN 439
            .:|.||.   :..:...||..::.  |.::.:.|||.:||..||..|...::|.:|.:.:
pombe   387 GSDSLVD---IQAMLNALPAEVEH--VKVDSYEHLDMIWADTVKDYVIPPVLRRLRDIHH 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	24/67 (36%)
		MhpC	93..436	CDD:223669	117/367 (32%)
		Abhydrolase_5	115..281	CDD:289465	67/176 (38%)
SPCC1672.09	NP_587880.1	Abhydro_lipase	81..145	CDD:282003	25/66 (38%)
SPCC1672.09	NP_587880.1	Abhydrolase_1	127..422	CDD:278959	99/317 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1506
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	11	10.800