DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31871 and lipl-5

DIOPT Version :9

Sequence 1:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_503184.1	Gene:	lipl-5 / 178563	WormBaseID:	WBGene00022642	Length:	403	Species:	Caenorhabditis elegans

Alignment Length:	376	Identity:	133/376 - (35%)
Similarity:	202/376 - (53%)	Gaps:	28/376 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 LITPKLIRKYGYPSETHTVVTKDGYILEMHRIP--------KKGAQPVLLM-HGILDTSATWVLM 132
            :.||::|.::|||:..:||.|.|||||||||||        ..|.:||:.| ||:|..|:.||:.
Worm    27 MTTPQIIERWGYPAMIYTVATDDGYILEMHRIPFGKTNVTWPNGKRPVVFMQHGLLCASSDWVVN 91

  Fly   133 GPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILSKT 197
            .|....|::.:|.|:|||:||.|||.||..|..|...:..|||:::.||..|||.|.|:::|..|
Worm    92 LPDQSAGFLFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEMATYDLNAMINHVLEVT 156

  Fly   198 GYEQVHYIGHSQGT-AIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFLDFLTAA 261
            |.:.|:|:|||||| .:|..|..:..::.:||....|||||..:..:|.        ||.|....
Worm   157 GQDSVYYMGHSQGTLTMFSHLSKDDGSFAKKIKKFFALAPIGSVKHIKG--------FLSFFANY 213

  Fly   262 TRM--------LRITEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVM 318
            ..:        ....||:||...:...::.:|....:..|:|.|:|||:||..|:|.|:|.:||.
Worm   214 FSLEFDGWFDIFGAGEFLPNNWAMKLAAKDICGGLKVEADLCDNVLFLIAGPESDQWNQTRVPVY 278

  Fly   319 LSHTPSGASIKQLEHFGQLMKSGHFRKFDRGYLRNQLEYNRMTPPDYDLSRVK-VPVALYYSVND 382
            .:|.|:|.|.:.:.|:.|::..|....:|.|...|:.:|.:..||:||.:.:| ..:.||:|..|
Worm   279 ATHDPAGTSTQNIVHWMQMVHHGGVPAYDWGTKTNKKKYGQANPPEYDFTAIKGTKIYLYWSDAD 343

  Fly   383 LLVSTTGV-DRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVR 432
            .|..|..| |.|...|...|......:..:|||||.|.:.....:|...::
Worm   344 WLADTPDVPDYLLTRLNPAIVAQNNHLPDYNHLDFTWGLRAPDDIYRPAIK 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	30/62 (48%)
		MhpC	93..436	CDD:223669	127/360 (35%)
		Abhydrolase_5	115..281	CDD:289465	63/175 (36%)
lipl-5	NP_503184.1	PLN02872	8..394	CDD:215470	133/374 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156612
Domainoid	1	1.000	220	1.000	Domainoid score	I1499
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	285	1.000	Inparanoid score	I1723
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm4823
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1506
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.940