DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dbf and Zfp385d

DIOPT Version :9

Sequence 1:	NP_609430.1	Gene:	dbf / 34462	FlyBaseID:	FBgn0287630	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017455135.2	Gene:	Zfp385d / 305691	RGDID:	1359606	Length:	447	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	84/434 - (19%)
Similarity:	140/434 - (32%)	Gaps:	145/434 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 QNQSHQLESAIKGLNGYTNVAQESEKPKNGYKYQPAAFADQRIVLQPKLGQGQGQAQG-AVPGFI 363
            |.:.|...:.....|...|.|.:::...||..:|...   :::.....:..|.|..|. |:|
  Rat    11 QEKKHSNFTFCSVCNIQLNSATQAQIHYNGKSHQKRL---KQLTKGVPMSDGGGTCQSPALP--- 69

  Fly   364 PNHLQSRVAMVEPRI--RQESL-IKPQNP---DLALPSEAHP-------------------PVPQ 403
                    |::.|..  .|.|| |||..|   |.|......|                   |:|.
  Rat    70 --------ALIHPPAPPLQPSLDIKPFLPFPLDTAATVNLFPNFNAMDPIQKAVINHTFGVPLPH 126

  Fly   404 DLQSLFRWNYCALCNMVIRSTQSAIDHYSSRAHERRISSW--------------LVRKCYANLT- 453
            ..:.:..   |.:|.:...|...|..||....|.:::.:.              ..:..:.::|
  Rat   127 RKKQIIS---CNICQLRFNSDSQAAAHYKGTKHAKKLKALESMKNKQKSVTAKDSAKTTFTSITT 188

  Fly   454 -------------------GRDAD-----------------ALGGAISQSE-------------- 468
                               .|.||                 :|..|::...
  Rat   189 NPITTSSDKTESTAGTQVIARSADMRKSSEVTTELTSNAEKSLTAAVAAGNNSSPPTETEEEKAK 253

  Fly   469 --FYCKLCDLKLTSLSHAQQHFLGRRHR--IAARH---RIRPFSDGFYDREG--NWVRTDI--KY 522
              .||.||.:.:.|.|..:.|..|.:|:  :.||:   .|:.|.......:|  |...|.:  |.
  Rat   254 RLLYCSLCKVAVNSASQLEAHNSGTKHKTMLEARNGSGTIKAFPRAGMKGKGPVNKGNTGLQNKT 318

  Fly   523 PMCELCDVIITSESQMAMHLAGARHRRRVQIAYAGESAGGMEMGIGLVPFD----GSHMYRIRGN 583
            ..||:|||.:.||:|:..|::..||:.|         |.|........|::    .:|...::..
  Rat   319 FHCEICDVHVNSETQLKQHISSRRHKDR---------ASGKPPKPKYSPYNKLQKAAHPLGVKLV 374

  Fly   584 GSLAPIRPLGSQLLQGSA------------YPLSL-TDPSAVFY 614
            .|..|.:||..::|....            .|.|| |.|:|..:
  Rat   375 FSKEPSKPLTPRILPNPLAAAAAAAAVAVNSPFSLRTAPAATLF 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbf	NP_609430.1	zf-met	524..547	CDD:289631	9/22 (41%)
dbf	NP_609430.1	ZnF_U1	613..640	CDD:197732	0/2 (0%)
Zfp385d	XP_017455135.2	zf-met	20..43	CDD:403930	5/22 (23%)
		C2H2 Zn finger	134..156	CDD:275371	6/21 (29%)
		zf-met	134..156	CDD:403930	6/21 (29%)
		YjdB	<184..282	CDD:227779	15/97 (15%)
		zf-met	256..280	CDD:403930	8/23 (35%)
		C2H2 Zn finger	258..320	CDD:275371	16/61 (26%)
		zf-met	319..343	CDD:403930	9/23 (39%)
		C2H2 Zn finger	321..343	CDD:275371	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342053
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.800