DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dbf and znf385a

DIOPT Version :9

Sequence 1:	NP_609430.1	Gene:	dbf / 34462	FlyBaseID:	FBgn0287630	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_009295234.1	Gene:	znf385a / 100147851	ZFINID:	ZDB-GENE-090313-255	Length:	423	Species:	Danio rerio

Alignment Length:	429	Identity:	89/429 - (20%)
Similarity:	149/429 - (34%)	Gaps:	133/429 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 PTVPRP----------AVKKPRHVAEL-----CLDSNGEYVLNKQLHQPLISRQPDPIIP----- 288
            |||.:|          .::.|.|...|     .:|...:.|:|.....||: :...|||.
Zfish    19 PTVIQPHLDMKPFLQFPMETPPHSVGLFHNFNAMDPVQKAVINHTFGVPLV-KTKRPIISCNVCQ 82

  Fly   289 ----SVSSRDPHYFIQNQSHQLESAIKGLNGYTNVAQESEKPKNGYKYQPAAFADQRIVLQPKLG 349
                |.|..:.||    :.::....:||:....:..||::|...|....|:
Zfish    83 IRFNSESQAEAHY----KGNRHARRVKGIETSKSRPQENDKTPPGPVSSPS-------------- 129

  Fly   350 QGQGQAQGAVPGFIPNHLQSRVAMVEPRIRQESLIKPQ--NPDLAL--PSEAHPPVPQDLQSLFR 410
                 ..||:| .||:        .:|....|:..:||  .|.:||  .:.::||.|:....
Zfish   130 -----PTGALP-TIPD--------TDPSKTDETRPEPQLNGPAVALGPMTVSNPPTPESPGP--- 177

  Fly   411 WNYCALCNMVIRSTQSAIDHYSSRAHERRISSWLVRKCYANLTGRDADALGGAIS------QSE- 468
                :.|.::...|.......||.:          ..|.::...:......||.|      ::|
Zfish   178 ----SACPLLPTPTTPQPPPASSSS----------PSCGSSNPEQAGTGAPGAPSVTPSNPETEE 228

  Fly   469 ------FYCKLCDLKLTSLSHAQQHFLGRRHR--IAARHRIRPFSDGFYDREG-----------N 514
                  .||.||.:.:.|||..:.|..|.:|:  :.||..:.|..  .|.|.|           .
Zfish   229 DKAKKLLYCSLCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIK--AYPRLGPKPSREQGGGAT 291

  Fly   515 WVRTDIKYPMCELCDVIITSESQMAMHLAGARHRRRV----------QIAYAGESAGGM--EMGI 567
            ...|..:...||:|:|.:.||.|:..|::..|||..|          ...:.|.....:  .:|.
Zfish   292 DPNTQERTFHCEICNVRVNSELQLKQHISSRRHRDGVAGKPNPLLSRHKKHRGADLADLTKALGA 356

  Fly   568 GLVPFDGSHMYRIRGNGSLAPIRPLGSQLLQGSAYPLSL 606
            ||:|               :|:....:.....|:.||:|
Zfish   357 GLLP---------------SPLAVAAAMAAAASSNPLAL 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbf	NP_609430.1	zf-met	524..547	CDD:289631	8/22 (36%)
dbf	NP_609430.1	ZnF_U1	613..640	CDD:197732
znf385a	XP_009295234.1	C2H2 Zn finger	78..100	CDD:275371	4/25 (16%)
		zf-met	78..100	CDD:289631	4/25 (16%)
		zf-met	236..259	CDD:289631	9/22 (41%)
		C2H2 Zn finger	237..259	CDD:275371	8/21 (38%)
		zf-met	301..324	CDD:289631	8/22 (36%)
		C2H2 Zn finger	302..324	CDD:275371	8/21 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582111
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.800