DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dbf and znf346

DIOPT Version :9

Sequence 1:	NP_609430.1	Gene:	dbf / 34462	FlyBaseID:	FBgn0287630	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_002936996.3	Gene:	znf346 / 100135716	XenbaseID:	XB-GENE-967544	Length:	354	Species:	Xenopus tropicalis

Alignment Length:	301	Identity:	62/301 - (20%)
Similarity:	106/301 - (35%)	Gaps:	74/301 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   366 HLQSRVAMVEPRIRQESLIKPQNPDLALPSEAHPPVPQDLQSLFRWNYCALCNMVIRSTQSAIDH 430
            |.|||....:.| |..|:.:.:....|...:|.|....|...  |...|.:|||...|...|..|
Frog    52 HYQSRKHANKVR-RYMSIHQGEELVSAKKFKAAPAESSDGDD--RSKCCPICNMTFSSPVVAESH 113

  Fly   431 YSSRAHERRI---------SSWL--VRKCYANLTGRDADALGGAISQSE--FYCKLCDLKLTSLS 482
            ||.:.|.:.:         ...|  .:|.....|...|..:...:.||:  .:||||.....:..
Frog   114 YSGKTHIKNLRLREQGGVTEGMLHQAKKLVVTRTPTIATKIDNRMDQSDPTKFCKLCHATFNNPL 178

  Fly   483 HAQQHFLGRRHRIAARHRIRPFSDGFYDREGNW-----VRTDIKYPM-----------CELCDVI 531
            .|:||:.|::|:   :...:......|...|:.     :..::..|:           |:.|:::
Frog   179 MAEQHYAGKKHK---KQETKTQLMTIYTSSGHTPAQAPIAINVNSPLPGSGSAGKGFSCDTCNIV 240

  Fly   532 ITSESQMAMHLAGARHRRRVQ----------------------------IAYAGESAGGMEMGIG 568
            :.|..|...|::||:|:.::.                            ::..|.||.|.....|
Frog   241 LNSIEQYQAHVSGAKHKNQLMSMTPLSKEGPPAAGGPSALAGPPSTGGALSSGGPSARGFSASGG 305

  Fly   569 LVPFDGSHMYRIRGNGSLAPIRPLGSQLLQGSAYPLSLTDP 609
            ..|         :|..|...:.|:|.  |....||...:.|
Frog   306 PTP---------KGPSSFGGLPPMGG--LMPPPYPPPHSQP 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbf	NP_609430.1	zf-met	524..547	CDD:289631	7/33 (21%)
dbf	NP_609430.1	ZnF_U1	613..640	CDD:197732
znf346	XP_002936996.3	ZnF_U1	36..65	CDD:197732	5/13 (38%)
		C2H2 Zn finger	36..58	CDD:275371	4/5 (80%)
		ZnF_U1	92..126	CDD:197732	11/35 (31%)
		C2H2 Zn finger	97..119	CDD:275371	9/21 (43%)
		ZnF_U1	165..195	CDD:197732	9/32 (28%)
		C2H2 Zn finger	167..189	CDD:275371	8/21 (38%)
		zf-met	232..256	CDD:403930	7/23 (30%)
		C2H2 Zn finger	234..256	CDD:275371	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565630at2759
OrthoFinder	1	1.000	-	-		FOG0001854
OrthoInspector	1	1.000	-	-		otm47911
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6359
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920