DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dbf and zmat4b

DIOPT Version :9

Sequence 1:	NP_609430.1	Gene:	dbf / 34462	FlyBaseID:	FBgn0287630	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017213517.2	Gene:	zmat4b / 100005974	ZFINID:	ZDB-GENE-091118-68	Length:	229	Species:	Danio rerio

Alignment Length:	261	Identity:	52/261 - (19%)
Similarity:	92/261 - (35%)	Gaps:	71/261 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   408 LFRWNYCALCNMVIRSTQSAIDHYSSRAHERRISSWLVRK-----CYANLTGRDADALGGAISQS 467
            ||..:||.:|:..:.|....:.||.||.|..::..:.:..     |.|.....|..:..|.:.::
Zfish    10 LFTDSYCKVCSAQLISESQRVAHYESRKHANKVRLYYMLHPVDGGCPAKKLRTDNGSADGDVDKN 74

  Fly   468 EFYCKLCDLKLTSLSHAQQHFLGRRHRIAARHRI----------------------RPFSDGFYD 510
            : .|.||::..||...||.|:.|:.|  |.|.|:                      ..:.||...
Zfish    75 K-CCTLCNMSFTSAVVAQSHYQGKIH--AKRLRLLLGEPAAIMSKEVTVEPDHMMDEDWKDGSPS 136

  Fly   511 REGNWVRTDIKYPMCELCDVIITSESQMAMHLAGARHRRRVQIAYAGESAGGMEMGIGLVPFDGS 575
            ..|.     :....|::|.....:......|..|.:|::.      |..|..:.. :|....||.
Zfish   137 TNGK-----LSQRYCQMCKAWFNNPGMARQHYNGKKHKKN------GAQANLLAQ-LGKTLEDGE 189

  Fly   576 HMYRIRGNGSLAPIRPLGSQLLQGSAYPLSLTDPSAVFYCDACNITLNHLKSVNQHEQGRMHRRN 640
            .|..::.:.:                             |:.|::|||.:...:.|.||..|:.|
Zfish   190 EMNGLKRSHT-----------------------------CEVCSVTLNSVAQYHAHLQGSKHQNN 225

  Fly   641 M 641
            :
Zfish   226 L 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dbf	NP_609430.1	zf-met	524..547	CDD:289631	4/22 (18%)
dbf	NP_609430.1	ZnF_U1	613..640	CDD:197732	9/26 (35%)
zmat4b	XP_017213517.2	ZnF_U1	15..45	CDD:197732	9/29 (31%)
		C2H2 Zn finger	16..38	CDD:275371	7/21 (33%)
		C2H2 Zn finger	77..99	CDD:275371	9/21 (43%)
		zf-met	77..99	CDD:315537	9/21 (43%)
		DUF3449	<111..>199	CDD:331240	14/99 (14%)
		ZnF_U1	142..171	CDD:197732	5/28 (18%)
		C2H2 Zn finger	146..168	CDD:275371	4/21 (19%)
		zf-met	199..222	CDD:315537	8/51 (16%)
		C2H2 Zn finger	200..222	CDD:275371	8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565630at2759
OrthoFinder	1	1.000	-	-		FOG0001854
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_170663
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820