DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17097 and Lipf

DIOPT Version :9

Sequence 1:	NP_609429.1	Gene:	CG17097 / 34461	FlyBaseID:	FBgn0265264	Length:	1087	Species:	Drosophila melanogaster
Sequence 2:	NP_059037.1	Gene:	Lipf / 50682	RGDID:	708441	Length:	395	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	122/370 - (32%)
Similarity:	192/370 - (51%)	Gaps:	37/370 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   729 LIEKYGYPSETNYVTSEDGYRLCLHRIPRP-------GAEPVL-LVHGLMASSASWVELGPKDGL 785
            :|..:|||.:...|.:||||.|.::|||..       |..||: |.|||:||:.:|:...|.:.|
  Rat    37 MITYWGYPCQEYEVVTEDGYILGVYRIPHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSL 101

  Fly   786 AYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYWDFSFHEIGKFDVPAAIDHILIHTHKPKIQ 850
            |::|...|||||:.|:|||.:||:|:.......::|.|||.|:.|:|:||.|:.|:..|.:.||.
  Rat   102 AFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQKTGQEKIH 166

  Fly   851 YIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVYLQENRSPVLK--FLGMFKGKYSMLLNLLG 913
            |:|||||:|:.|:..|..|..|.|:....||:|...::..:||:.|  |:..|      |..|:.
  Rat   167 YVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTF------LFKLMF 225

  Fly   914 GYEISAKTKLIQQFRQHICSGSELGSSICA--IFD-------FVLCGFDWKSFNTTLTPIVAAHA 969
            |.::         |..|......||:.:|:  :.|       |:.||||.|:.|.:...:...|.
  Rat   226 GKKM---------FLPHTYFDDFLGTEVCSREVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHN 281

  Fly   970 SQGASAKQIYHYAQLQGDLNFQRFDHGA-VLNRVRYESSEPPAYNLSQTTSKVVLHHGEGDWLGS 1033
            ..|.|.:...|:|||.....||.|:.|: ..|.:.|....||.|::|..|..|.:.:|..|.|..
  Rat   282 PAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSAMTVPVAVWNGGNDILAD 346

  Fly  1034 TSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYSHVL 1078
            ..||..|..:|.||:..:::  ..::|.||..:.|....:|:.::
  Rat   347 PQDVAMLLPKLSNLLFHKEI--LAYNHLDFIWAMDAPQEVYNEMI 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	23/58 (40%)
		MhpC	746..1061	CDD:223669	111/334 (33%)
		Abhydrolase_5	762..>899	CDD:289465	58/139 (42%)
Lipf	NP_059037.1	PLN02872	4..389	CDD:215470	122/368 (33%)
		Abhydro_lipase	34..96	CDD:282003	23/58 (40%)
		Abhydrolase_5	77..>221	CDD:289465	59/149 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335505
Domainoid	1	1.000	229	1.000	Domainoid score	I2382
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850