DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17097 and Lip3

DIOPT Version :9

Sequence 1:	NP_609429.1	Gene:	CG17097 / 34461	FlyBaseID:	FBgn0265264	Length:	1087	Species:	Drosophila melanogaster
Sequence 2:	NP_477331.1	Gene:	Lip3 / 41643	FlyBaseID:	FBgn0023495	Length:	394	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	133/372 - (35%)
Similarity:	199/372 - (53%)	Gaps:	29/372 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   730 IEKYGYPSETNYVTSEDGYRLCLHRIP----------RPGAEPVLLVHGLMASSASWVELGPKDG 784
            ||..|||.|.:.|.:.|.|.|.:||||          ||.|   .|:||:::||:.||.:||:..
  Fly    32 IEDDGYPMERHEVVTSDNYILTMHRIPYSPKTGESSNRPVA---FLMHGMLSSSSDWVLMGPERS 93

  Fly   785 LAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKY--------WDFSFHEIGKFDVPAAIDHIL 841
            |||:|...||||||.|.|||.||        |.:||        |:||::|||.:||||.||::|
  Fly    94 LAYMLADAGYDVWMGNARGNTYS--------KAHKYWPTYWQIFWNFSWNEIGMYDVPAMIDYVL 150

  Fly   842 IHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVYLQENRSPVLKFLGMFKGKYS 906
            ..|.:.::||:|||||:||:.||.||||.|..|:.....|.|..|:...:||:.:......|:.:
  Fly   151 AKTGQQQVQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAPILGQPN 215

  Fly   907 MLLNLLGGYEISAKTKLIQQFRQHICSGSELGSSICAIFDFVLCGFDWKSFNTTLTPIVAAHASQ 971
            .::.:.|..|.....|..|.....:|..:...:.:||...|::.|:|.:..:..|...:.|.:..
  Fly   216 AIVEVCGSMEFMPSNKFKQDLGIEMCQATSPYADMCANEIFLIGGYDTEQLDYELLEHIKATSPA 280

  Fly   972 GASAKQIYHYAQLQGDLNFQRFDHGAVLNRVRYESSEPPAYNLSQTTSKVVLHHGEGDWLGSTSD 1036
            |||..|..|:.|......|::||:.|:.|...|.|..||.|.|....:.|:|::|..||:...||
  Fly   281 GASVNQNLHFCQEYNSGKFRKFDYTALRNPYEYGSYFPPDYKLKNAKAPVLLYYGANDWMCDVSD 345

  Fly  1037 VIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYSHVLRHLST 1083
            |.:|::.|||:.....|.||.::|.||....:.|..:|..||:.:.:
  Fly   346 VRKLRDELPNMALDYLVPFEKWAHLDFIWGTEARKYVYDEVLKQMQS 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	24/59 (41%)
		MhpC	746..1061	CDD:223669	119/332 (36%)
		Abhydrolase_5	762..>899	CDD:289465	64/144 (44%)
Lip3	NP_477331.1	PLN02872	26..392	CDD:215470	133/370 (36%)
		Abhydro_lipase	30..89	CDD:282003	24/59 (41%)
		Abhydrolase_5	74..>192	CDD:289465	60/125 (48%)
		Abhydrolase_5	<315..355	CDD:289465	15/39 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439471
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850