Protein Alignment CG17097 and LIPA

DIOPT Version :9

• Sequence 1: NP_609429.1
• Gene: CG17097 / 34461
• FlyBaseID: FBgn0265264
• Length: 1087
• Species: Drosophila melanogaster
• Sequence 2: NP_000226.2
• Gene: LIPA / 3988
• HGNCID: 6617
• Length: 399
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 124/377 - (32%)
• Similarity: 195/377 - (51%)
• Gaps: 30/377 - (7%)

  Fly   723 KLTTVD---------LIEKYGYPSETNYVTSEDGYRLCLHRIPR-------PGAEPVL-LVHGLM 770
            |||.||         :|..:|:|||...|.:||||.|||:|||.       .|.:||: |.|||:
Human    25 KLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLL 89

  Fly   771 ASSASWVELGPKDGLAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYWDFSFHEIGKFDVPA 835
            |.|::||.......|.:||...|:||||.|:|||.:||::....:..:::|.||:.|:.|:|:||
Human    90 ADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPA 154

  Fly   836 AIDHILIHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVYLQENRSPVLKFLGM 900
            :|:.||..|.:.::.|:|||||:|:.|:..|:.|..|.::.:..||.|...:....||:.| ||.
Human   155 SINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAK-LGR 218

  Fly   901 FKGKYSMLLNLLGGYEISAKTKLIQQFRQHICSG---SELGSSICAIFDFVLCGFDWKSFNTTLT 962
            ...  .::.:|.|..|...::..::....|:|:.   .||..::|    |:||||:.::.|.:..
Human   219 LPD--HLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLC----FLLCGFNERNLNMSRV 277

  Fly   963 PIVAAHASQGASAKQIYHYAQLQGDLNFQRFDHG-AVLNRVRYESSEPPAYNLSQTTSKVVLHHG 1026
            .:...|:..|.|.:.:.|::|......||.||.| :..|...|..|.||.||:........:..|
Human   278 DVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSG 342

  Fly  1027 EGDWLGSTSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYSHVL 1078
            ..|||....||..|..::.|||....:  ..:.|.||....|....||:.::
Human   343 GHDWLADVYDVNILLTQITNLVFHESI--PEWEHLDFIWGLDAPWRLYNKII 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	29/70 (41%)
		MhpC	746..1061	CDD:223669	106/326 (33%)
		Abhydrolase_5	762..>899	CDD:289465	53/137 (39%)
LIPA	NP_000226.2	PLN02872	38..396	CDD:215470	119/364 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141852
Domainoid	1	1.000	222	1.000	Domainoid score	I2592
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.850