DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17097 and Lipk

DIOPT Version :9

Sequence 1:	NP_609429.1	Gene:	CG17097 / 34461	FlyBaseID:	FBgn0265264	Length:	1087	Species:	Drosophila melanogaster
Sequence 2:	XP_017444545.1	Gene:	Lipk / 294094	RGDID:	1309724	Length:	402	Species:	Rattus norvegicus

Alignment Length:	387	Identity:	122/387 - (31%)
Similarity:	199/387 - (51%)	Gaps:	23/387 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   715 QEDILD---NTKLTTV---DLIEKYGYPSETNYVTSEDGYRLCLHRIPR---------PGAEPVL 764
            ||.|.:   |..:..:   ::|..:|||.|.:.|.:||||.|..:|||.         |.| .|.
  Rat    21 QESITNPEANMNIVCIFQSEIISYWGYPYERHDVVTEDGYILGTYRIPHGKGCSRKAVPKA-VVY 84

  Fly   765 LVHGLMASSASWVELGPKDGLAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYWDFSFHEIG 829
            |.|||:||:::|:...|.:.||::|...|||||:.|:|||.:||::|....|..:||.||..|:.
  Rat    85 LQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLRLSPKSPEYWAFSLDEMA 149

  Fly   830 KFDVPAAIDHILIHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVYLQENRSPV 894
            |:|:||.|:.||..:.:.::.|:|||||:|:.|:..|..|..|.|:.:..||:|.|.::..:||:
  Rat   150 KYDLPATINLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRMFFALAPVVTVKYTQSPM 214

  Fly   895 LKFLGMFKGKYSMLLNLLGGYEISAKTKLIQQFRQHICSGSELGSSICAIFDFVLCGFDWKSFNT 959
            .|...:.:....:   |.|....|..|.|.|.....:|: .:|...:|:.|.|.|.|||.::.|.
  Rat   215 KKLTTLSRKAVKI---LFGDKMFSTHTWLEQFIATKVCN-RKLFRQLCSNFLFSLSGFDPQNLNM 275

  Fly   960 TLTPIVAAHASQGASAKQIYHYAQLQGDLNFQRFDHG-AVLNRVRYESSEPPAYNLSQTTSKVVL 1023
            :...:..|.:..|.|.:.:.|:||.......|.||.| ...|.:.:....||.||:|:......:
  Rat   276 SRLDVYMAQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAM 340

  Fly  1024 HHGEGDWLGSTSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYSHVLRHLSTSL 1085
            ..|..|.:....|...|..::.||:..:::  ..::|.||.|.:|....:|..::..:..||
  Rat   341 WSGGRDVVADEKDTKNLLPKVANLIYYKEI--PHYNHMDFYLGQDAPQEVYRDLITMMEESL 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	24/65 (37%)
		MhpC	746..1061	CDD:223669	103/324 (32%)
		Abhydrolase_5	762..>899	CDD:289465	56/136 (41%)
Lipk	XP_017444545.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335541
Domainoid	1	1.000	229	1.000	Domainoid score	I2382
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850