DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17097 and Lipa

DIOPT Version :9

Sequence 1:	NP_609429.1	Gene:	CG17097 / 34461	FlyBaseID:	FBgn0265264	Length:	1087	Species:	Drosophila melanogaster
Sequence 2:	NP_036864.3	Gene:	Lipa / 25055	RGDID:	3008	Length:	397	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	126/393 - (32%)
Similarity:	197/393 - (50%)	Gaps:	37/393 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   697 INVVTPEYKVFKTPNYLTQEDILDNTKLTTVDLIEKYGYPSETNYVTSEDGYRLCLHRIPR---- 757
            |:.|.||                  ..:...::|..:|||.|.:.|.:.|||.|.:||||.
  Rat    24 ISAVDPE------------------ANMNVTEIIMHWGYPGEEHSVQTGDGYILGVHRIPHGRKN 70

  Fly   758 ---PGAEPVL-LVHGLMASSASWVELGPKDGLAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPN 818
               .|.:||: |.||.:|.|::||.....:.|.:||...|:||||.|:|||.:||::....:..:
  Rat    71 QFDKGPKPVVYLQHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQD 135

  Fly   819 KYWDFSFHEIGKFDVPAAIDHILIHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSP 883
            :||.|||.|:.|:|:||:|::||..|.:.::.|:|||||.|:.|:..|:.|..|.||.:..||:|
  Rat   136 EYWAFSFDEMAKYDLPASINYILNKTGQEQLYYVGHSQGCTIGFIAFSQMPELAKKVKMFFALAP 200

  Fly   884 TVYLQENRSPVLKFLGMFKGKYSMLL--NLLGGYEISAKTKLIQQFRQHICSGSELGSSICAIFD 946
            .:.|.....|::|.     |:...||  :|.|..:...::.:::....|||: ..:...:||...
  Rat   201 VLSLNFASGPMVKL-----GRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICT-HVIMKELCANIF 259

  Fly   947 FVLCGFDWKSFNTTLTPIVAAHASQGASAKQIYHYAQLQGDLNFQRFDHGAV-LNRVRYESSEPP 1010
            |::|||:.|:.|.:...:...|...|.|.:.:.|:.|:......|.||.|:. .|...|..|.||
  Rat   260 FLICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPP 324

  Fly  1011 AYNLSQTTSKVVLHHGEGDWLGSTSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYS 1075
            .|::........|..|..|||..|||:..|...:|.||..:  |...:.|.||....|....||:
  Rat   325 LYSIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLVYHK--NIPEWDHLDFIWGLDAPWRLYN 387

  Fly  1076 HVL 1078
            .|:
  Rat   388 EVV 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	24/61 (39%)
		MhpC	746..1061	CDD:223669	109/325 (34%)
		Abhydrolase_5	762..>899	CDD:289465	56/137 (41%)
Lipa	NP_036864.3	PLN02872	7..394	CDD:215470	126/393 (32%)
		Abhydro_lipase	35..96	CDD:282003	24/60 (40%)
		Abhydrolase_5	78..>203	CDD:289465	53/124 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335565
Domainoid	1	1.000	229	1.000	Domainoid score	I2382
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850