DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and TGL1

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_012782.1	Gene:	TGL1 / 853717	SGDID:	S000001623	Length:	548	Species:	Saccharomyces cerevisiae

Alignment Length:	387	Identity:	109/387 - (28%)
Similarity:	175/387 - (45%)	Gaps:	51/387 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 DIQIDAKLETP----KMISKYGHQVETHYAFTADGYKLCLHRIP-----RSGATPVLLVHGLMAS 145
            |..|:.||.:.    :|.:.:...||.|...|.|.|.|.|||||     |.....|.|.|||:..
Yeast    53 DNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNKVVYLHHGLLMC 117

  Fly   146 SATW-VQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAA 209
            |..| ......:.|.::|...||||||.|.|||.||...|........|||||..|...:|:|.:
Yeast   118 SDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDEFAFFDIPNS 182

  Fly   210 IDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKLF 274
            |:.||..||:..:..||.||||...|...|...:...|:|...:::|::..:|..:..:..:...
Yeast   183 IEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHNRIVDTLAKS 247

  Fly   275 SGGFTMLLNLLGGHKISLKNKIVDMFRNH---------ICTKLIPSRICAIFEFVVCGFNFNSFN 330
            |.||   :.|..|.||.|.:.::.....|         |..|::              ||:.|||
Yeast   248 SPGF---MYLFFGRKIVLPSAVIWQRTLHPTLFNLCIDIANKIL--------------FNWKSFN 295

  Fly   331 MTLSPILEGHAS--QGSSAKQIYHFAQLQGNSAFQKYDYG-LILNKIR--YQ-SIFPPLYNLSLA 389
            :.....:..:|.  ..:|.|.|.|:.|:..:..||.::.. .:||.:.  || :.||...|:.:.
Yeast   296 ILPRQKIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEESDNMLNSLTRPYQIANFPTRTNIKIP 360

  Fly   390 LGKVALHRGDGDWLGSESDVLRLERDLP-NCIENRNIRFEGFSHFDFTISKDVRSLVYDRVI 450
            :  :.::.|    :.|..|:..::::|| |.:  .:::.:.:.|.|....||..:||..:|:
Yeast   361 I--LLIYGG----IDSLVDIDVMKKNLPFNSV--FDVKVDNYEHLDLIWGKDADTLVIAKVL 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	21/60 (35%)
		PLN02872	101..450	CDD:215470	104/370 (28%)
		Abhydrolase_5	135..>250	CDD:289465	44/115 (38%)
TGL1	NP_012782.1	Abhydro_lipase	66..124	CDD:397965	21/57 (37%)
TGL1	NP_012782.1	Abhydrolase_1	106..402	CDD:395444	86/320 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I1188
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870