DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and MPL1

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_568295.2	Gene:	MPL1 / 831268	AraportID:	AT5G14180	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	378	Identity:	111/378 - (29%)
Similarity:	174/378 - (46%)	Gaps:	60/378 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 YGHQVETHYAFTADGYKLCLHRIP--RSGAT--------PVLLVHGLMASSATWVQFGPSQGLAY 160
            :|::.|.|...|.|||.|.:.|||  |:||.        |||:.||::....:|:.....|.|..
plant    59 FGYKCEEHDVVTQDGYILNMQRIPEGRAGAVAGDGGKRQPVLIQHGILVDGMSWLLNPADQNLPL 123

  Fly   161 ILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSIQYI 225
            ||:..|:||||.||||..:|........|.:.||::::.|:..|||||..|.|...|.. .|.|:
plant   124 ILADQGFDVWMGNTRGTRFSRRHKYLNPSQRAFWNWTWDELVSYDLPAMFDHIHGLTGQ-KIHYL 187

  Fly   226 GHSQGSTAFFVMCSERPEYAGKISLMQS---LSPSVYMEGTRSPALKFMKLFSGGF---TML--- 281
            |||.|:...|...||:    |.:..::|   |||..|        |..|....|..   |.|
plant   188 GHSLGTLIGFASFSEK----GLVDQVRSAAMLSPVAY--------LSHMTTVIGDIAAKTFLAEA 240

  Fly   282 LNLLGGHKISLKNKIVDMFRNHICTK----------LIPSRICAIFEFVVCGFNFNSFNMTLSPI 336
            .::||..:.:.|:.:|..|...||.|          :|..:.|.:        |.::.::.|:
plant   241 TSILGWPEFNPKSGLVGDFIKAICLKAGIDCYDLVSVITGKNCCL--------NASTIDLFLA-- 295

  Fly   337 LEGHASQGSSAKQIYHFAQLQGNSAFQKYDYGLILNKIR-YQSIFPPLYNLSLALGKVALHRGDG 400
               :..|.:|.|.:.|.||...:...:||:||.....|: |....||.||:|....::.|....|
plant   296 ---NEPQSTSTKNMIHLAQTVRDKELRKYNYGSSDRNIKHYGQAIPPAYNISAIPHELPLFFSYG 357

  Fly   401 --DWLGSESDV-LRLERDLPNCIENRNIRF-EGFSHFDFTISKDVRSLVYDRV 449
              |.|....|| ..|::...:.|:..|::| :.::|.||.:....:.:||::|
plant   358 GLDSLADVKDVEFLLDQFKYHDIDKMNVQFVKDYAHADFIMGVTAKDVVYNQV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	19/53 (36%)
		PLN02872	101..450	CDD:215470	111/378 (29%)
		Abhydrolase_5	135..>250	CDD:289465	42/114 (37%)
MPL1	NP_568295.2	PLN02872	16..415	CDD:215470	111/378 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D651396at2759
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.070