DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18284 and Lipf

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_080610.1	Gene:	Lipf / 67717	MGIID:	1914967	Length:	395	Species:	Mus musculus

Alignment Length:	369	Identity:	121/369 - (32%)
Similarity:	197/369 - (53%)	Gaps:	16/369 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 DAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIP-------RSGATPV-LLVHGLMASSATWV 150
            :|.:...:||:.:|:..|.:...|.|||.|.::|||       ..|..|| .|.|||:||:..|:
Mouse    29 EANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWI 93

  Fly   151 QFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILL 215
            ...|:..||:||:.:|||||:.|:|||.:|.:.:........||.|||.|:.:|||||.||.|:.
Mouse    94 TNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATIDFIVQ 158

  Fly   216 QTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKLFSGGFTM 280
            :|....|.|:|||||:|..|:..|..|..|.||....:|:|...::.|.||..|...:..    .
Mouse   159 KTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIPK----F 219

  Fly   281 LLNLLGGHKISLKNKIVDMF-RNHICTKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQG 344
            ||.::.|:|:.:.:..:|.| ...:|::.:...:|:...|:.|||:..:.|::...:..||...|
Mouse   220 LLKVIFGNKMFMPHNYLDQFLGTEVCSRELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHNPAG 284

  Fly   345 SSAKQIYHFAQLQGNSAFQKYDYGLIL-NKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESD 408
            :|.:.::|:|||..:...|.|::|..| |.:.|....||.|::|.....:|:..|..|.|....|
Mouse   285 TSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILADPQD 349

  Fly   409 VLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVISL 452
            |..|...|||.:.::.|.  .::|.||..:.|....||:.::::
Mouse   350 VAMLLPKLPNLLYHKEIL--PYNHLDFIWAMDAPQEVYNEIVTM 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	21/58 (36%)
		PLN02872	101..450	CDD:215470	120/358 (34%)
		Abhydrolase_5	135..>250	CDD:289465	53/115 (46%)
Lipf	NP_080610.1	PLN02872	35..389	CDD:215470	120/359 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.910