DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and lipa

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	368	Identity:	111/368 - (30%)
Similarity:	179/368 - (48%)	Gaps:	16/368 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 DAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIPR------SGATPVL-LVHGLMASSATWVQ 151
            :|.:...::|...|:..|.:...|.|||.|.::|||.      .|..||: |.|||:|..:.||.
Frog    44 EATMNISELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVT 108

  Fly   152 FGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQ 216
            ...:..|.:||:.:|||||:.|:|||.:|.:..:.....:.||.||:.|:.:.||||.:|.|..:
Frog   109 NLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKK 173

  Fly   217 TKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKL--FSGGFT 279
            |....|.|:|||||:|..|:..|..|:.|.||.:...|:|...::.::||..|...|  |
Frog   174 TGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEF----- 233

  Fly   280 MLLNLLGGHKISLKNKIVDMFRNHICTKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQG 344
            ::..|.|..:...:..::.....|.||..|...:|....|::.|||..:.||:...:...|...|
Frog   234 LIEELFGKGEFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCPAG 298

  Fly   345 SSAKQIYHFAQLQGNSAFQKYDYGLILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESDV 409
            :|.:.:.|:.|...:...:.:|:|...|.|.|....||.|::.......||..|..|||....||
Frog   299 TSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDV 363

  Fly   410 LRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVISL 452
            ..|...:.|.:.::.|  ..:.|.||....|....:|:.:|::
Frog   364 ALLLTQVSNLVYHKEI--PDWEHLDFIWGLDAPERMYNEIIAM 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	19/57 (33%)
		PLN02872	101..450	CDD:215470	109/357 (31%)
		Abhydrolase_5	135..>250	CDD:289465	48/115 (42%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	21/60 (35%)
		PLN02872	50..409	CDD:215470	110/362 (30%)
		Abhydrolase_5	91..>229	CDD:289465	53/137 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.030