DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and Lipn

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001178884.1	Gene:	Lipn / 499345	RGDID:	1560354	Length:	398	Species:	Rattus norvegicus

Alignment Length:	377	Identity:	120/377 - (31%)
Similarity:	187/377 - (49%)	Gaps:	16/377 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 FAEVDIQIDAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIP-------RSGATPVL-LVHGL 142
            |.|..:..:..:...::|:..|:..|.:...|||||.|.::|||       .:|..||: :.|.|
  Rat    23 FFENTVNPEVWMNASEIITYNGYPSEEYDVTTADGYILAINRIPHGRGQTGHAGPRPVVYMQHAL 87

  Fly   143 MASSATWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLP 207
            .|.:|.|::..|:..|.::|:.:||||||.|:|||.:|........:::.||.|||.|:.:||||
  Rat    88 FADNAYWLENFPNGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEKFWAFSFDEMAKYDLP 152

  Fly   208 AAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMK 272
            ..||.|:.:|....:.:||||.|:|..|:..|..||.|.:|.:..:|.|.:   ..:.|...|..
  Rat   153 GIIDFIVNKTGQEKLYFIGHSLGTTIGFIAFSTMPELAQRIKMNFALGPVI---SFKYPTSIFTS 214

  Fly   273 LFSGGFTMLLNLLGGHKISLKNKIVDMFRNHICTKLIPSRICAIFEFVVCGFNFNSFNMTLSPIL 337
            .|....:|:..:.|.....|::|...|....:|.|.:...:|:.|..:..|||..:.||:...:.
  Rat   215 FFLLPRSMIKLMFGTKGFFLEDKNAKMSYVTVCNKKLLRPMCSEFMSLWAGFNKKNMNMSRLDVY 279

  Fly   338 EGHASQGSSAKQIYHFAQLQGNSAFQKYDYGL-ILNKIRYQSIFPPLYNLSLALGKVALHRGDGD 401
            ..||..|||.:.|.|..||..:..|:.||:|. ..|...|....||||:|:......|:..|..|
  Rat   280 MSHAPTGSSIQNILHIKQLYQSDEFRAYDWGSEAENMNHYNQSRPPLYDLTAMKVPTAIWAGGHD 344

  Fly   402 WLGSESDVLRLERDLPNCIENRNIR-FEGFSHFDFTISKDVRSLVYDRVISL 452
            .|.:..||.|:   ||.....|..: |..::||||....|....:|.::|.|
  Rat   345 VLVTPQDVARI---LPQITNLRYFKQFPEWNHFDFVWGLDAPQRLYSKIIGL 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	19/58 (33%)
		PLN02872	101..450	CDD:215470	116/358 (32%)
		Abhydrolase_5	135..>250	CDD:289465	47/115 (41%)
Lipn	NP_001178884.1	Abhydro_lipase	37..97	CDD:282003	20/59 (34%)
Lipn	NP_001178884.1	Abhydrolase_1	79..379	CDD:278959	101/305 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.960