DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and CG2772

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	127/382 - (33%)
Similarity:	187/382 - (48%)	Gaps:	25/382 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 VDIQIDAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIPRS-------------GATPVLLV- 139
            :||.......:.:.|:::|:..|:|:..|.|||.|.:.|||.|             .:.||:|:
  Fly    25 IDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIM 89

  Fly   140 HGLMASSATWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQY 204
            |||.:.|..::..||...|.|..:.:|||||:.|.|||:||............||.||:||||..
  Fly    90 HGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSI 154

  Fly   205 DLPAAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYM-EGTRSPAL 268
            ||||.||.||.:|...|:.|:|||||.|:||||.|.||||..||.....|:|.||| ..|....:
  Fly   155 DLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIV 219

  Fly   269 KFMKLFSG---GFTMLLNLLGGHKISLKNKIVDMFRNHICT-KLIPSRICAIFEFVVCGFNFNSF 329
            ....||..   |.|:|.|.:    :..:|..:....:..|: :.|....|.....:..|....:.
  Fly   220 STAPLFGHHGIGSTLLENQV----LLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNL 280

  Fly   330 NMTLSP-ILEGHASQGSSAKQIYHFAQLQGNSAFQKYDYGLILNKIRYQSIFPPLYNLSLALGKV 393
            |.||.| |.|.|.: |.|:.|..|:.|...::.|:.||:|...|...|....||.|:|:....::
  Fly   281 NQTLLPQIAETHPA-GVSSNQAIHYIQSYASNDFRLYDWGSKRNLEYYGVSEPPAYDLTKITSEL 344

  Fly   394 ALHRGDGDWLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVI 450
            .|:.|..|...::.|:.||...|||......:....:.|.||..:.:|:.::.|.|:
  Fly   345 YLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVL 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	20/64 (31%)
		PLN02872	101..450	CDD:215470	124/368 (34%)
		Abhydrolase_5	135..>250	CDD:289465	58/115 (50%)
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	124/372 (33%)
		Abhydro_lipase	36..103	CDD:282003	20/66 (30%)
		Abhydrolase	113..>196	CDD:304388	45/82 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439489
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900