DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and Lipm

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_220066.4	Gene:	Lipm / 309528	RGDID:	1304912	Length:	422	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	114/368 - (30%)
Similarity:	190/368 - (51%)	Gaps:	14/368 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 DAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIPR-------SGATP-VLLVHGLMASSATWV 150
            :|.:...::|...|:..|.:...|.|||.|.::||||       .|:.| |||.|||:..::.|:
  Rat    44 EAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTQLKKEGSRPVVLLQHGLLGDASNWI 108

  Fly   151 QFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILL 215
            ...|:..|.:||:.:|:||||.|:|||.:|.:..........||.||:.|:.::||||.|:.||.
  Rat   109 SNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQ 173

  Fly   216 QTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKLFSGGFTM 280
            :|....|.|:|:|||:|..|:..|..||.|.||.:..:|:|...::..:||..||:.|..   .|
  Rat   174 KTGQKKIYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKHAKSPGTKFLLLPD---MM 235

  Fly   281 LLNLLGGHKISLKNKIVDMFRNHICTKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQGS 345
            :..|.|..:...:.:.......::|.::|..:||:....::.|||.|:.||:.:.:...|...|:
  Rat   236 IKGLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGT 300

  Fly   346 SAKQIYHFAQLQGNSAFQKYDYGL-ILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESDV 409
            |.:.|.|::|...:...:.:|:|. ..|:.:.....|..|.:...:...|:..|..|||.:..||
  Rat   301 SVQNILHWSQAVNSGELRAFDWGSETKNREKSNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDV 365

  Fly   410 LRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVISL 452
            ..|..::.|.|.::||  ..::|.||....|....||:.:|.|
  Rat   366 KTLLSEVTNLIYHKNI--PEWAHVDFIWGLDAPHRVYNEIIHL 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	20/58 (34%)
		PLN02872	101..450	CDD:215470	111/357 (31%)
		Abhydrolase_5	135..>250	CDD:289465	49/115 (43%)
Lipm	XP_220066.4	Abhydro_lipase	49..111	CDD:282003	21/61 (34%)
		Abhydrolase_1	92..392	CDD:278959	95/304 (31%)
		Abhydrolase_5	93..>231	CDD:289465	54/137 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.860