DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18284 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	487	Identity:	123/487 - (25%)
Similarity:	197/487 - (40%)	Gaps:	121/487 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IAFNIAIYAIILVG---SLVPSKTQEW------VPYAYPVDE--NQGLNEQTQWQSQSQIQSQGT 56
            ||..:.:|..::..   .::|.:.:||      |.|.|.:..  ..|:.:..|
pombe    18 IAAFVGVYTELVARIFIYMIPERVREWFRVRIIVLYHYYISSKTTDGMTDAVQ------------ 70

  Fly    57 SQSQSQAQIQSQPEPRSCLQCQQASYQQFFAEVDIQIDAKLETPKMISKYGHQVETHYAFTADGY 121
                               :|:.. |:                  :...:|::||.|...|.|.:
pombe    71 -------------------KCRNI-YE------------------ICEAFGYRVEEHLVRTQDNF 97

  Fly   122 KLCLHRI--PRSG---ATPVLLVHGLMASSATWVQFGPSQ-GLAYILSQSGYDVWMLNTRGNVYS 180
            .||||||  |:..   ...|...||||.:|..||....|: .|.::|.:||||||:.|.|||.||
pombe    98 ILCLHRITHPKQSQHKREVVYCHHGLMTNSELWVAVNESERSLPFVLIESGYDVWLGNNRGNKYS 162

  Fly   181 EERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYA 245
            .:.:..:..|:.||:||..::..:|:|..:|.||.:|....:.|||.|||:.......|..|:..
pombe   163 RKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYILRETGREKLNYIGFSQGTAQAMAALSINPDLN 227

  Fly   246 GKISLMQSLSPSVYMEGTRSPALKFMKLFSGGFTMLLNLLGGHKISLKNKIVDMFRNHICTKLIP 310
            .|:::...|:|:...:|           ||..|.       .:.:.:..||:.......|  |:|
pombe   228 DKVNIFIGLAPAYAPKG-----------FSNYFV-------DYIVKVNPKIMYHLFGRRC--LLP 272

  Fly   311 S-----RIC--AIFEFVV-----CGFNFNSFNMTLSPILEG--HASQGSSAKQIYHFAQLQGNSA 361
            |     .||  .||..:|     ..||::..|::|:..|.|  |....||.|.:.|:.|:..|..
pombe   273 SVTFWQNICYPPIFVKIVDVSLKILFNWDLSNISLNQKLCGYAHLYSFSSVKSVVHWLQIIKNCT 337

  Fly   362 FQKYDYGLIL----NKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSES----DVLRLERDLPN 418
            ||.||..:.|    ....||....|..|:...:  :.|      |.|.::    :|:|..  ||.
pombe   338 FQLYDDDMALLAGYGSRHYQVPLFPTNNIKCPM--LIL------WGGKDTLINMEVMRTA--LPP 392

  Fly   419 CIENRNIRFEGFSHFDFTISKDVRSLVYDRVI 450
              ..:.:....:.|.||...:||:..|:..||
pombe   393 --HAKEVSIAHYEHLDFLWGQDVKEEVFPVVI 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	19/55 (35%)
		PLN02872	101..450	CDD:215470	108/376 (29%)
		Abhydrolase_5	135..>250	CDD:289465	43/115 (37%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	20/74 (27%)
		Abhydrolase_1	116..410	CDD:278959	92/325 (28%)
		Abhydrolase	<171..>242	CDD:304388	22/70 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870