DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and Lipk

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001192278.1	Gene:	Lipk / 240633	MGIID:	2679259	Length:	403	Species:	Mus musculus

Alignment Length:	371	Identity:	115/371 - (30%)
Similarity:	183/371 - (49%)	Gaps:	34/371 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 KMISKYGHQVETHYAFTADGYKLCLHRIPR--------SGATPVLLVHGLMASSATWVQFGPSQG 157
            ::||.:|:..|.|...|.|||.|..:|||.        :....|.|.|||:||:..|:...|:..
Mouse    41 ELISYWGYPYEKHDVITEDGYILGTYRIPHGKGCSRKTAPKAVVYLQHGLIASANNWICNLPNNS 105

  Fly   158 LAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSI 222
            ||::|:.||||||:.|:|||.:|...|........:|.||:.|:.:|||||.::|||.::....:
Mouse   106 LAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEMAKYDLPATVNLILEKSGQKQL 170

  Fly   223 QYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKLFSGGFTMLLNLLGG 287
            .|:|||||:|..|:..|..||.|.||.|..:|:|...::.||||..|...|    ....:.:|.|
Mouse   171 FYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRSPMKKLTTL----SRKAVKVLFG 231

  Fly   288 HKISLKNKIVDMFRNH----------ICTKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHAS 342
            .|         ||..|          :|.:.:..::|:.|.|.:.||:..:.||:...:....:.
Mouse   232 DK---------MFSTHTWFEQFIATKVCNRKLFHQLCSNFLFSLSGFDPQNLNMSRLDVYLSQSP 287

  Fly   343 QGSSAKQIYHFAQLQGNSAFQKYDYG-LILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSE 406
            .|:|.:.:.|:||...:...|.:|:| ...|.:.:..:.||:||:|......|:..|..|.:...
Mouse   288 AGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGQDVVADA 352

  Fly   407 SDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVISL 452
            .|...|...:.|.|..:.|  ..::|.||.:.:|....||..:|.:
Mouse   353 KDTKNLLPKIANLIYYKEI--PHYNHMDFYLGQDAPQEVYGDLIRM 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	20/56 (36%)
		PLN02872	101..450	CDD:215470	114/367 (31%)
		Abhydrolase_5	135..>250	CDD:289465	50/114 (44%)
Lipk	NP_001192278.1	Abhydro_lipase	40..101	CDD:282003	21/59 (36%)
		Abhydrolase_5	82..>210	CDD:289465	53/127 (42%)
		Abhydrolase_1	83..382	CDD:278959	98/313 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.910