DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18284 and LOC100360690

DIOPT Version :9

Sequence 1:	NP_001285807.1	Gene:	CG18284 / 34460	FlyBaseID:	FBgn0043825	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_006231366.1	Gene:	LOC100360690 / 100360690	RGDID:	2321667	Length:	399	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	119/376 - (31%)
Similarity:	183/376 - (48%)	Gaps:	33/376 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 DAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIP---------RSGATPVL-LVHGLMASSAT 148
            :|.:...::||.:|::.|.|...|.|||.|.:.|||         .:...||: |.|||..|:..
  Rat    29 EANMNVSQIISYWGYESEEHEVMTEDGYILLIFRIPHGKNENKSSHNTRRPVVYLHHGLTVSADY 93

  Fly   149 WVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLI 213
            |:...||..||::|:.:|::||:.|:||...:.:.:......|.||||||:|..:|||||.|..|
  Rat    94 WILDPPSNCLAFLLADAGFEVWLGNSRGTNNARKHVRLDPDSKEFWDFSFNEQIEYDLPAIIYFI 158

  Fly   214 LLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKLFSGGF 278
            |.:|:...|.|||||||....:...:..|:.|.||.:..:|.|.|           ..|..:|.|
  Rat   159 LNETRQTQIYYIGHSQGVYLAYAAFATNPQLAQKIKINFALGPVV-----------ITKYLTGVF 212

  Fly   279 --------TMLLNLLGGHKISLKNKIVDMFRNHICTKLIPSRICAIFEFVVCGFNFNSFNMTLSP 335
                    |::..:.|...|..|:...|:.| .:|.:...:..|.....|:.|:|..:.|.:...
  Rat   213 RTIAYIHPTVIKTMFGEKDIFSKSNANDILR-FLCHREQIATACTSLLIVLFGYNPGNLNESRID 276

  Fly   336 ILEGHASQGSSAKQIYHFAQLQGNSAFQKYDYGL-ILNKIRYQSIFPPLYNLSLALGKVALHRGD 399
            :...|...|:|.:.|.||:|...:..||.||:|. .||.:.|....||:||:.....:.|:..|:
  Rat   277 VYSEHIPAGTSVRSILHFSQGIRSGLFQAYDWGSESLNVLHYNQSTPPIYNIEDMKVRTAMWSGE 341

  Fly   400 GDWLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVI 450
            .|.||...||..|....||.|.::.|  ..::|.||.:.||....||.::|
  Rat   342 RDLLGDPKDVKNLAAKTPNLIYHKKI--PHYNHMDFILGKDAVVQVYRKII 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18284	NP_001285807.1	Abhydro_lipase	99..150	CDD:282003	20/60 (33%)
		PLN02872	101..450	CDD:215470	117/367 (32%)
		Abhydrolase_5	135..>250	CDD:289465	48/115 (42%)
LOC100360690	XP_006231366.1	Abhydro_lipase	34..96	CDD:282003	21/61 (34%)
		Abhydrolase_1	79..378	CDD:278959	100/312 (32%)
		Abhydrolase_5	79..245	CDD:289465	60/177 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.960