Protein Alignment CG31872 and LIPA

DIOPT Version :10

• Sequence 1: NP_723603.1
• Gene: CG31872 / 34458
• FlyBaseID: FBgn0051872
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_001427765.1
• Gene: LIPA / 3988
• HGNCID: 6617
• Length: 443
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 121/376 - (32%)
• Similarity: 193/376 - (51%)
• Gaps: 16/376 - (4%)

  Fly   703 ITEVDIEIDAKLDTPKMISKYGHQAETHYAFTADGYKLCLHRIPR-------SGATPVL-LVHGL 759
            :|.||.|  ..::..::||.:|..:|.:...|.|||.|||:|||.       .|..||: |.|||
Human    70 LTAVDPE--TNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGL 132

  Fly   760 MASSDTWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLP 824
            :|.|..||....:..|.:||:.:|:||||.|:|||.:|.:......|...||.||:.|:.:||||
Human   133 LADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLP 197

  Fly   825 AAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMK 889
            |:|:.||.:|....:.|:|||||:|..|:..|:.||.|.:|.:..:|.|...:....||..|..:
Human   198 ASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGR 262

  Fly   890 VLQGGFTMLLNLLGGHKISLKNRIVDMFRNHICNKLIPSRICAIFEFVVCGFNFNSFNMTLSPIL 954
            :..   .::.:|.|..:...::..:.....|:|..:|...:|....|::||||..:.||:...:.
Human   263 LPD---HLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVY 324

  Fly   955 EGHASQGSSAKQIYHFAQLQGNSAFQKYDYG-LILNKIRYQSIFPPLYNLSLALGKVALHRGDGD 1018
            ..|:..|:|.:.:.|::|......||.:|:| ...|...|...:||.||:...|...|:..|..|
Human   325 TTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHD 389

  Fly  1019 WLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVIDL 1069
            ||....||..|...:.|.:.:.:|  ..:.|.||....|....:|:::|:|
Human   390 WLADVYDVNILLTQITNLVFHESI--PEWEHLDFIWGLDAPWRLYNKIINL 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31872	NP_723603.1	Smc	<220..>485	CDD:440809
		PLN02872	718..1067	CDD:215470	115/357 (32%)
LIPA	NP_001427765.1	None