DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31872 and CG11406

DIOPT Version :9

Sequence 1:	NP_001285806.1	Gene:	CG31872 / 34458	FlyBaseID:	FBgn0051872	Length:	1073	Species:	Drosophila melanogaster
Sequence 2:	NP_001014548.1	Gene:	CG11406 / 37877	FlyBaseID:	FBgn0034990	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	133/420 - (31%)
Similarity:	197/420 - (46%)	Gaps:	47/420 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   657 APNERQSQLQSQRQDQDQGPKFDDDLDEQPAPRSCSQCQKASYPQYITEVDIEIDAKLDTPKMIS 721
            ||.|.:.:.:..|          |.|    ..||.|.||.....|.
  Fly     2 APEEEEPEEEVAR----------DSL----CTRSDSVCQAVQRQQL------------------- 33

  Fly   722 KYGHQAETHYAFTADGYKLCLHRIPR-------SGATPVLLVHGLMASSDTWVQFGPSQGLAYIL 779
                |.:.|...|||||:|.|||||.       ....|.||:|||:.|:..:|..|..:.||..|
  Fly    34 ----QCQVHRIETADGYRLSLHRIPAPQNRWCPQQLRPFLLMHGLLGSAGDFVSGGRGRSLALEL 94

  Fly   780 SQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSIQYIGH 844
            ....:|||:.|.||..:|......:.||..||.||:||||.|||||.:|.:|.:|....:.|:||
  Fly    95 HARCFDVWLANARGTTHSRGHRTLQTSDARFWRFSWHEIGIYDLPAIVDYVLARTNRRQLHYVGH 159

  Fly   845 SQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKVLQGGFTMLLNLLGGHKISL 909
            |||:|...|:.|:||||..:.:....|:|..:::...||.|:.:.......|:|||.||.|::..
  Fly   160 SQGTTVLLVLLSQRPEYNARFANAALLAPVAFLQHLSSPPLRLLASDSSMATLLLNKLGLHELLP 224

  Fly   910 KNRIVDMFRNHICNKLIPS-RICAIFEFVVCGFNFNSFNMTLSPILEGHASQGSSAKQIYHFAQL 973
            .:.:..:.....|....|: .:|.:|..|..||:....:.::.|.:......|.|..|:.||.||
  Fly   225 ASALTQVGGQFFCTASRPTYALCTLFTSVYVGFSDYPLDRSILPRILETTPAGISRGQLQHFGQL 289

  Fly   974 QGNSAFQKYDY-GLILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESDVLRLERDLPNCI 1037
            ..:..||:||| ...||.:||....||.|.|:....::.:..|..|.|.|.:||.||.|:|.|.:
  Fly   290 INSGKFQQYDYRSPRLNTLRYGRTTPPSYQLANVRLQLQIFHGSRDTLSSLADVQRLVRELRNSV 354

  Fly  1038 ENRNIRFEGFSHFDFTISKDVRSLVYDRVI 1067
             .:..:..|::|.||..:.....:|:.|:|
  Fly   355 -TQMYQVPGYNHIDFLFASSAPQVVFQRII 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31872	NP_001285806.1	Abhydro_lipase	716..767	CDD:282003	20/57 (35%)
CG31872	NP_001285806.1	Abhydrolase_5	752..>894	CDD:289465	55/141 (39%)
CG11406	NP_001014548.1	Abhydro_lipase	28..85	CDD:282003	22/79 (28%)
		Abhydrolase_1	67..371	CDD:278959	105/304 (35%)
		Abhydrolase_5	67..>203	CDD:289465	55/135 (41%)
		Abhydrolase_5	<315..365	CDD:289465	16/50 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439430
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850