DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31872 and SPBC14C8.15

DIOPT Version :9

Sequence 1:	NP_001285806.1	Gene:	CG31872 / 34458	FlyBaseID:	FBgn0051872	Length:	1073	Species:	Drosophila melanogaster
Sequence 2:	NP_595918.1	Gene:	SPBC14C8.15 / 2539842	PomBaseID:	SPBC14C8.15	Length:	460	Species:	Schizosaccharomyces pombe

Alignment Length:	400	Identity:	105/400 - (26%)
Similarity:	176/400 - (44%)	Gaps:	49/400 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   696 KASYPQYITEVDIEIDA-KL----DTPKMISKYGHQAETHYAFTADGYKLCLHRI--PRSG---- 749
            |..|..::.|:.::.:| ||    ||..:.:.:|:..|.|:..|.|||.|.|||:  .:.|
pombe    50 KKVYSYFLPELLVDDNANKLTDARDTIDLCALHGYDLEEHFVRTTDGYLLGLHRVYKKKKGKIEE 114

  Fly   750 ---ATPVLLVHGLMASSDTWV-QFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIF 810
               ..|||.:||||.:|::|| .......:.:.|.:.|||||:.|.|||.||.:.:.....:..|
pombe   115 LNYLPPVLFIHGLMMNSESWVCNLKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPKF 179

  Fly   811 WDFSFHEIGQYDLPAAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSV 875
            ||||...|..:|:|:.:..||......||..:|.|||:...|...|...|....:....:|:|::
pombe   180 WDFSLDSIAIFDIPSIVKYILSVNSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPAI 244

  Fly   876 YMEGTRSPALKFMKVLQGGFTMLLNLLGGHKISLKNRIVDMFRNHICNKLIPSRICAIFEFVVCG 940
               ..:..:.:.:|.:....:.||.|:.|....|.:.:   |...:....:.::|..:|......
pombe   245 ---APKKYSGRTVKSIIHANSQLLYLMFGRNSMLGSAV---FWQAVLYPPVFAKIVDLFLRFFLS 303

  Fly   941 FNFNSFNMTLSPILEGHASQGSSAKQIYHFAQLQGNSAFQKYD--------YGLILNKI-RYQSI 996
            :...:.:.|...:...|....:|.|...|:||:......|.||        |...||:| ||
pombe   304 WTGKNISETQKIVAYSHLYSFTSVKCFVHWAQITRRKVLQMYDDSPGFKPSYYTNLNRIARY--- 365

  Fly   997 FPPLYNLSLALGKVALHRGDGDWLGSESDVLRLERDLP---NCIENRNIRFEGFSHFDFTISKDV 1058
              |:.|:.|   .:.|..|..|   :..|:..|:..||   .||:..|     :.|.|..:....
pombe   366 --PIENIRL---PITLVYGSND---NMVDIETLKTQLPPLSQCIQIPN-----YEHLDIIMGDTK 417

  Fly  1059 RSLVYDRVID 1068
            :.:|..:|::
pombe   418 KDIVIQQVVE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31872	NP_001285806.1	Abhydro_lipase	716..767	CDD:282003	21/59 (36%)
CG31872	NP_001285806.1	Abhydrolase_5	752..>894	CDD:289465	44/142 (31%)
SPBC14C8.15	NP_595918.1	Abhydro_lipase	75..138	CDD:282003	23/62 (37%)
		Abhydrolase_1	119..412	CDD:278959	83/314 (26%)
		Abhydrolase_5	120..>260	CDD:289465	44/142 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810