DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31872 and Lipa

DIOPT Version :9

Sequence 1:	NP_001285806.1	Gene:	CG31872 / 34458	FlyBaseID:	FBgn0051872	Length:	1073	Species:	Drosophila melanogaster
Sequence 2:	NP_001104570.1	Gene:	Lipa / 16889	MGIID:	96789	Length:	397	Species:	Mus musculus

Alignment Length:	376	Identity:	123/376 - (32%)
Similarity:	194/376 - (51%)	Gaps:	16/376 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   703 ITEVDIEIDAKLDTPKMISKYGHQAETHYAFTADGYKLCLHRIPR-------SGATPVL-LVHGL 759
            ::.||.|::  ::..::|.::|:..|.|...|.|||.|.:|||||       .|..||: |.|||
Mouse    24 VSAVDPEVN--MNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGL 86

  Fly   760 MASSDTWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLP 824
            :|.|..||....:..|.::|:.:|:||||.|:|||.:|.:......|...||.|||.|:.:||||
Mouse    87 LADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLP 151

  Fly   825 AAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMK 889
            |:|:.||.:|....|.|:|||||.|..|:..|:.||.|.||.:...|:|.:.:.....|.|:..:
Mouse   152 ASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGR 216

  Fly   890 VLQGGFTMLLNLLGGHKISLKNRIVDMFRNHICNKLIPSRICAIFEFVVCGFNFNSFNMTLSPIL 954
            :..   .:|.::.|..:...::.::.....|:|..:|...:||...|::||||..:.||:...:.
Mouse   217 LPD---PLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVY 278

  Fly   955 EGHASQGSSAKQIYHFAQLQGNSAFQKYDYGLI-LNKIRYQSIFPPLYNLSLALGKVALHRGDGD 1018
            ..|...|:|.:.:.|:.|:......|.:|:|.. .|...|...|||.||:.......||..|..|
Mouse   279 TTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRD 343

  Fly  1019 WLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVIDL 1069
            ||...:|:..|...:|..:.::||  ..:.|.||....|....:||.:|.|
Mouse   344 WLADINDITILLTQIPKLVYHKNI--PEWDHLDFIWGLDAPWKLYDEIISL 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31872	NP_001285806.1	Abhydro_lipase	716..767	CDD:282003	23/58 (40%)
CG31872	NP_001285806.1	Abhydrolase_5	752..>894	CDD:289465	57/142 (40%)
Lipa	NP_001104570.1	PLN02872	6..394	CDD:215470	123/376 (33%)
		Abhydro_lipase	35..96	CDD:282003	25/60 (42%)
		Abhydrolase_5	78..>192	CDD:289465	51/113 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831893
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850