DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7329 and Lipm

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_076392.1	Gene:	Lipm / 78753	MGIID:	1926003	Length:	422	Species:	Mus musculus

Alignment Length:	412	Identity:	130/412 - (31%)
Similarity:	213/412 - (51%)	Gaps:	54/412 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVVLGIYTLD---GSGVLGGFMENTYPASVIE-DAHLNTIQLLEKYKHPAETHQVTTDDKYILTL 68
            |::|..|.|.   .||.|        |....: :|.:|..::::...:|:|.::|.|:|.|||::
Mouse    19 LLILVAYLLQRNVNSGHL--------PTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSV 75

  Fly    69 HRIAR-------PGAKP-VLLVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKG 125
            :||.|       .|::| |||.|||...:|.||...|.:.||:.|...|:||||||.|||.:|:.
Mouse    76 NRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRK 140

  Fly   126 HVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNA 190
            |..|:.:.|: :|:||:.|:..:||||:|:.:|||||.:|:.|.|:|||||..|:..|:.||...
Mouse   141 HKTLSIDQDE-FWAFSYDEMARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAH 204

  Fly   191 KIHLMSALAPVAFMKHMKAPLMGIARMGMNMFGDNFELFP-------------------HSEVFL 236
            ||.:..||||:|.:|:.::|            |..|.|.|                   ..::|:
Mouse   205 KIKMYFALAPIATVKYARSP------------GTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFI 257

  Fly   237 NQCLSSAAMLKTCMRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYD 301
            ..| ....:.:.|......:.|.|....||:...|.:.|.|.|.:::..||:.|...|.....:|
Mouse   258 YLC-GQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFD 321

  Fly   302 YESK-ENQRLYGRSTPPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRKWNH 365
            :.|: :||....:.||..|::..:..|.|::.|..|:||..:||..|...:.|::.:....:|.|
Mouse   322 WGSETKNQEKCNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAH 386

  Fly   366 MDMIWGISARRSIQPRILQVMQ 387
            :|.|||:.|.:.:...|:.:|:
Mouse   387 VDFIWGLDAPQRVYNEIIHLMK 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	22/61 (36%)
		Abhydrolase	73..239	CDD:304388	70/192 (36%)
		Abhydrolase_1	77..371	CDD:278959	103/314 (33%)
Lipm	NP_076392.1	PLN02872	50..408	CDD:215470	119/371 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831838
Domainoid	1	1.000	227	1.000	Domainoid score	I2491
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H28267
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8736
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.810