DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and Lipf

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_080610.1	Gene:	Lipf / 67717	MGIID:	1914967	Length:	395	Species:	Mus musculus

Alignment Length:	375	Identity:	129/375 - (34%)
Similarity:	206/375 - (54%)	Gaps:	36/375 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRI-------ARPGAKPV-LLVHGLEDTSSTWI 93
            :|::|..|::..:.:|:|.::|.|:|.|||.::||       ...|.:|| .|.|||..:::.||
Mouse    29 EANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWI 93

  Fly    94 VMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVL 158
            ...|.:.|.:.|...|||||:||.|||.:|:.:|..:|:: ..:|:||:.|:..|||||.||.::
Mouse    94 TNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDS-VEFWAFSFDEMAKYDLPATIDFIV 157

  Fly   159 QKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMKAPLMGIARM------ 217
            ||||.:|:.|.|||||||..|:..|:.|....||....||||||.:|:.::|...|:.:
Mouse   158 QKTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIPKFLLK 222

  Fly   218 ---GMNMFGDNFELFPHS--EVFLNQCLSSAAMLK-TCMRFYWQIVGKNREEQNMTMFPVVLGHL 276
               |..||      .||:  :.||...:.|..:|. .|....:...|.:::..|::.|.|.|||.
Mouse   223 VIFGNKMF------MPHNYLDQFLGTEVCSRELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHN 281

  Fly   277 PGGCNIKQALHYLQMQKSDRFCQYDYESK-ENQRLYGRSTPPDYRLERIKAPVALYYGSNDYLSA 340
            |.|.:.:...|:.|:.||.:...|::.|. :|...|.:.|||.|.:..:..|:|::.|.:|.|:.
Mouse   282 PAGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILAD 346

  Fly   341 VEDVHRLAKVLPNVVENHLYRK----WNHMDMIWGISARRSIQPRILQVM 386
            .:||..|...|||:    ||.|    :||:|.||.:.|.:.:...|:.:|
Mouse   347 PQDVAMLLPKLPNL----LYHKEILPYNHLDFIWAMDAPQEVYNEIVTMM 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	20/61 (33%)
		Abhydrolase	73..239	CDD:304388	70/177 (40%)
		Abhydrolase_1	77..371	CDD:278959	111/311 (36%)
Lipf	NP_080610.1	PLN02872	35..389	CDD:215470	125/364 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831808
Domainoid	1	1.000	227	1.000	Domainoid score	I2491
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8736
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.810