DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and lipa

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	387	Identity:	131/387 - (33%)
Similarity:	211/387 - (54%)	Gaps:	31/387 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GVLGGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRI------ARPGAKP 78
            ||.|..:.:..|     :|.:|..:|:....:|:|.::|.|:|.|||:::||      |..|.||
Frog    32 GVAGDLLYSADP-----EATMNISELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKP 91

  Fly    79 VL-LVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSW 142
            |: |.|||....|.|:.....:.||:.|...|||||:||.|||.:|:.|..|:|:.:: :|:||:
Frog    92 VVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEE-FWAFSY 155

  Fly   143 HEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHM 207
            .|:...||||::|.:.:|||.:::.|.|||||||..|:..||.|:...||.:...|||||.:|..
Frog   156 DELAKKDLPAVVDFITKKTGQEQIFYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFS 220

  Fly   208 KAPLMGIARMGM-------NMFGDNFELFPHSEVFLNQCLSS-----AAMLKTCMRFYWQIVGKN 260
            |:||   |::|:       .:||.. |..|  :.:|...|::     |...:.|...::.:.|.|
Frog   221 KSPL---AKLGVLPEFLIEELFGKG-EFLP--QTYLITWLATHFCTHAIADELCGNIFFLLSGFN 279

  Fly   261 REEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESKENQRLYGRSTPPDYRLERIK 325
            .:..||:...|...|.|.|.:::..||:.|..:|.....:|:.:|.|...|.::|||.|.:..:.
Frog   280 EKNLNMSRVNVYSSHCPAGTSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMT 344

  Fly   326 APVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRKWNHMDMIWGISARRSIQPRILQVMQ 387
            .|.||:.|.||:|:..:||..|...:.|:|.:.....|.|:|.|||:.|...:...|:.:|:
Frog   345 VPTALWTGGNDWLADRKDVALLLTQVSNLVYHKEIPDWEHLDFIWGLDAPERMYNEIIAMMK 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	22/60 (37%)
		Abhydrolase	73..239	CDD:304388	69/173 (40%)
		Abhydrolase_1	77..371	CDD:278959	107/306 (35%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	22/60 (37%)
		PLN02872	50..409	CDD:215470	125/364 (34%)
		Abhydrolase_5	91..>229	CDD:289465	61/141 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I2528
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm47739
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.030