DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and Lipf

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_059037.1	Gene:	Lipf / 50682	RGDID:	708441	Length:	395	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	135/405 - (33%)
Similarity:	222/405 - (54%)	Gaps:	41/405 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILVVLGIYTLDGSGVLGGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRI 71
            :|:...|.|..|:..|.|.:....|     :|::|..|::..:.:|.:.::|.|:|.|||.::||
  Rat     4 LLITSVISTFGGAHGLFGKLGPGNP-----EANMNISQMITYWGYPCQEYEVVTEDGYILGVYRI 63

  Fly    72 ARP-------GAKPVL-LVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVK 128
            ...       |.:||: |.|||..:::.||...|.:.|.:.|...|||||:||.|||.:|:.:|.
  Rat    64 PHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRGNTWSRKNVY 128

  Fly   129 LNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIH 193
            .:|:: ..:|:||:.|:..|||||.|:.::||||.:|:.|.|||||||..|:..|:.|....||.
  Rat   129 YSPDS-VEFWAFSFDEMAKYDLPATINFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPTLAKKIK 192

  Fly   194 LMSALAPVAFMKHMKAPLMGIA---------RMGMNMFGDNFELFPHS--EVFLNQCLSSAAMLK 247
            ...||||||.:|:.::||..|:         ..|..||      .||:  :.||...:.|..:|.
  Rat   193 TFYALAPVATVKYTQSPLKKISFIPTFLFKLMFGKKMF------LPHTYFDDFLGTEVCSREVLD 251

  Fly   248 -TCMRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYES-KENQRL 310
             .|....:...|.:::..|::.|.|.|||.|.|.:::..||:.|:.:|.:|..:::.| .:|...
  Rat   252 LLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLH 316

  Fly   311 YGRSTPPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRK----WNHMDMIWG 371
            |.:.|||:|.:..:..|||::.|.||.|:..:||   |.:||. :.|.|:.|    :||:|.||.
  Rat   317 YNQKTPPEYDVSAMTVPVAVWNGGNDILADPQDV---AMLLPK-LSNLLFHKEILAYNHLDFIWA 377

  Fly   372 ISARRSIQPRILQVM 386
            :.|.:.:...::.:|
  Rat   378 MDAPQEVYNEMISMM 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	19/61 (31%)
		Abhydrolase	73..239	CDD:304388	70/184 (38%)
		Abhydrolase_1	77..371	CDD:278959	112/311 (36%)
Lipf	NP_059037.1	PLN02872	4..389	CDD:215470	134/400 (34%)
		Abhydro_lipase	34..96	CDD:282003	19/61 (31%)
		Abhydrolase_5	77..>221	CDD:289465	62/144 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335509
Domainoid	1	1.000	229	1.000	Domainoid score	I2382
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8975
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810