DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and Lipn

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001178884.1	Gene:	Lipn / 499345	RGDID:	1560354	Length:	398	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	130/396 - (32%)
Similarity:	203/396 - (51%)	Gaps:	52/396 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRI-------ARPGAKPVL 80
            |||.|||    |..:..:|..:::....:|:|.:.|||.|.|||.::||       ...|.:||:
  Rat    21 GGFFENT----VNPEVWMNASEIITYNGYPSEEYDVTTADGYILAINRIPHGRGQTGHAGPRPVV 81

  Fly    81 -LVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHE 144
             :.|.|...::.|:...|...||:.|...||||||||.|||.:|:.|..|:.|.:| :|:||:.|
  Rat    82 YMQHALFADNAYWLENFPNGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEK-FWAFSFDE 145

  Fly   145 IGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMKA 209
            :..||||.:||.::.|||.:||.:.|||.|||..|:..|:.||...:|.:..||.||...|:
  Rat   146 MAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFIAFSTMPELAQRIKMNFALGPVISFKY--- 207

  Fly   210 PLMGIARMGMNMFGDNFELFPHSEV-------------------FLNQCLSSAAMLKTCMRFYWQ 255
                    ..::| .:|.|.|.|.:                   ::..| :...:...|..|...
  Rat   208 --------PTSIF-TSFFLLPRSMIKLMFGTKGFFLEDKNAKMSYVTVC-NKKLLRPMCSEFMSL 262

  Fly   256 IVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESK-ENQRLYGRSTPPDY 319
            ..|.|::..||:...|.:.|.|.|.:|:..||..|:.:||.|..||:.|: ||...|.:|.||.|
  Rat   263 WAGFNKKNMNMSRLDVYMSHAPTGSSIQNILHIKQLYQSDEFRAYDWGSEAENMNHYNQSRPPLY 327

  Fly   320 RLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYR---KWNHMDMIWGISARRSIQPR 381
            .|..:|.|.|::.|.:|.|...:||   |::||.:.....::   :|||.|.:||:.|.:.:..:
  Rat   328 DLTAMKVPTAIWAGGHDVLVTPQDV---ARILPQITNLRYFKQFPEWNHFDFVWGLDAPQRLYSK 389

  Fly   382 ILQVMQ 387
            |:.:|:
  Rat   390 IIGLMK 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	17/61 (28%)
		Abhydrolase	73..239	CDD:304388	62/185 (34%)
		Abhydrolase_1	77..371	CDD:278959	105/317 (33%)
Lipn	NP_001178884.1	Abhydro_lipase	37..97	CDD:282003	17/59 (29%)
Lipn	NP_001178884.1	Abhydrolase_1	79..379	CDD:278959	105/316 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335519
Domainoid	1	1.000	229	1.000	Domainoid score	I2382
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.010