DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and Lip1

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001285811.1	Gene:	Lip1 / 43973	FlyBaseID:	FBgn0023496	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	168/379 - (44%)
Similarity:	226/379 - (59%)	Gaps:	18/379 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRIARPGAKPVLLVHGLEDTSSTWIVMGP 97
            ::.:|:.|:..:|:.||.:.:|.|.|||:|.||||:|||.:.||.|.||.|||.|:|:.::||||
  Fly    59 NIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRIRKQGAPPFLLQHGLVDSSAGFVVMGP 123

  Fly    98 ESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTG 162
            ...|.|.|..:.||||:||.||||||:.|..|:|:..| :|.||||||||||||||||.||:.||
  Fly   124 NVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESK-FWDFSWHEIGMYDLPAMIDHVLKVTG 187

  Fly   163 YQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMK-APLMGIARMGMN-MFGDN 225
            :.||.|.|||||.||||||.|.||.||.|:..|.||||..:.|..: .|.:....:..| :.|.:
  Fly   188 FPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAISLYFNSLVGSS 252

  Fly   226 F-ELFPHSEVFLNQCLSSAAMLKTCMRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYL 289
            . |:|.....||  |..:....:.|:...:.|||:|..|.|..||||:|||.|.|...||..|::
  Fly   253 IREMFNGEFRFL--CRMTEETERLCIEAVFGIVGRNWNEFNRKMFPVILGHYPAGVAAKQVKHFI 315

  Fly   290 QMQKSDRFCQYDYESKENQRLYGRSTPPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNV 354
            |:.||.||..|.|.|.:|.:||....||.|.|..:..|..:||.:||.|...:||..:...|.||
  Fly   316 QIIKSGRFAPYSYSSNKNMQLYRDHLPPRYNLSLVTVPTFVYYSTNDLLCHPKDVESMCDDLGNV 380

  Fly   355 VENHL--YRKWNHMDMIWGISARRSIQPRILQVMQYWETGGGGTKDGTTGSPVE 406
            ...:|  .:::||||.:|.|..|:.:..|:|||:       |...:   |||.|
  Fly   381 TGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQVL-------GKVPE---GSPEE 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	27/53 (51%)
		Abhydrolase	73..239	CDD:304388	87/168 (52%)
		Abhydrolase_1	77..371	CDD:278959	136/298 (46%)
Lip1	NP_001285811.1	Abhydro_lipase	71..122	CDD:282003	27/50 (54%)
Lip1	NP_001285811.1	Abhydrolase_1	103..399	CDD:278959	136/298 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438265
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm26515
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900