DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and CG31871

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	171/368 - (46%)
Similarity:	231/368 - (62%)	Gaps:	19/368 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRIARPGAKPVLLVHGLEDTSSTWIVMG 96
            :.|:|||.|.|.:|:.||.:|:|||.|.|.|.|||.:|||.:.||:||||:||:.|||:||::||
  Fly    69 SDVLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIPKKGAQPVLLMHGILDTSATWVLMG 133

  Fly    97 PESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKT 161
            |:|||||.|...||||||||.|||||||.|..||.:. :.:|.|::||:|.|||||.||.:|.||
  Fly   134 PKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDY-QEFWDFTFHEMGKYDLPANIDYILSKT 197

  Fly   162 GYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMKAPLM-----------GIA 215
            ||:::.|.||||||..|:|:.|.:|.|..||..|.||||:|::..||:||.           ...
  Fly   198 GYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFLDFLTAAT 262

  Fly   216 RM-GMNMFGDNFE-LFPHSEVFLNQCLSSAAMLKTCMRFYWQIVGKNREEQNMTMFPVVLGHLPG 278
            || .:..|..|.: |..||:|.   |..:|.....|....:.:.|.|.|:.|.||.||:|.|.|.
  Fly   263 RMLRITEFMPNTKFLVDHSQVV---CHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLSHTPS 324

  Fly   279 GCNIKQALHYLQMQKSDRFCQYDYESKENQRLYGRSTPPDYRLERIKAPVALYYGSNDYLSAVED 343
            |.:|||..|:.|:.||..|.::|.....||..|.|.|||||.|.|:|.||||||..||.|.:...
  Fly   325 GASIKQLEHFGQLMKSGHFRKFDRGYLRNQLEYNRMTPPDYDLSRVKVPVALYYSVNDLLVSTTG 389

  Fly   344 VHRLAKVLPNVVENHL--YRKWNHMDMIWGISARRSIQPRILQ 384
            |.|||:.||||::.:|  ..::||:|.:|.|..:..:..|:::
  Fly   390 VDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVR 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	30/53 (57%)
		Abhydrolase	73..239	CDD:304388	89/178 (50%)
		Abhydrolase_1	77..371	CDD:278959	144/308 (47%)
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	30/53 (57%)
		MhpC	93..436	CDD:223669	159/344 (46%)
		Abhydrolase_5	115..281	CDD:289465	84/166 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438250
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	1	1.000	-	-		H28267
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm26515
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	12	11.800