DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and CG18301

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_609419.1	Gene:	CG18301 / 34451	FlyBaseID:	FBgn0032265	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	181/397 - (45%)
Similarity:	256/397 - (64%)	Gaps:	32/397 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LGIYTLDGSGVLGGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRIARPG 75
            ||::.|:.:.....| :...|:||:||||||||||:.||.:|||.:.|.:||.|:|.|.||||||
  Fly    16 LGLFQLEANAFFNPF-QLAIPSSVLEDAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRIARPG 79

  Fly    76 AKPVLLVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSF 140
            |.||||||||.|:|.||::|||.|.|||.||..||||||.|||||.|:|.||:.:.. |..:|:|
  Fly    80 ALPVLLVHGLMDSSDTWVMMGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAE-DSDFWNF 143

  Fly   141 SWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMK 205
            |:||:|::||||:||.:|.::|:.:|.|.|||||:|.|:::||.||||..||.:|.|||||||:.
  Fly   144 SFHEMGIFDLPAIIDYILMQSGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLS 208

  Fly   206 HMKAPLMG------------IARMGMNMF------GDNFELFPHSEVFLNQCLSSAAMLKTCMRF 252
            |.::|::.            ::..|.|.|      .|.|:.:...::     :||:    .|...
  Fly   209 HCRSPIVNLLASQDTAVASFLSAAGYNEFLPSNSVIDQFKRYACRDI-----ISSS----VCQSL 264

  Fly   253 YWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESKENQRLYGRSTPP 317
            ::.:.|.|.::.|.||.|:|:||.|.|.:|:|..||.|::.|.:|.|:|| ...|...||..:||
  Fly   265 FFILFGFNGQQVNQTMLPIVVGHTPAGASIRQMHHYGQLRNSGKFQQFDY-GLLNFLHYGSLSPP 328

  Fly   318 DYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLY--RKWNHMDMIWGISARRSIQP 380
            .|.||::||.||:||..||:::..|||..|...||||||.:|.  ..:||.|::||..|:|.:..
  Fly   329 PYELEKVKAKVAIYYAKNDWIAPPEDVDMLFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWN 393

  Fly   381 RILQVMQ 387
            |:|.|||
  Fly   394 RMLGVMQ 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	34/53 (64%)
		Abhydrolase	73..239	CDD:304388	87/183 (48%)
		Abhydrolase_1	77..371	CDD:278959	137/313 (44%)
CG18301	NP_609419.1	Abhydro_lipase	46..100	CDD:282003	34/53 (64%)
		PLN02872	48..407	CDD:215470	166/364 (46%)
		Abhydrolase_5	82..225	CDD:289465	78/143 (55%)
		Abhydrolase_5	<327..379	CDD:289465	25/51 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438239
Domainoid	1	1.000	56	1.000	Domainoid score	I18152
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	1	1.000	-	-		H28267
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm26515
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	12	11.800