DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7329 and Lipm

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_220066.4	Gene:	Lipm / 309528	RGDID:	1304912	Length:	422	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	132/397 - (33%)
Similarity:	216/397 - (54%)	Gaps:	24/397 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVVLGIYTLDGSGVLGGFMENTYPASVIE-DAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRI 71
            |::|..|.|. ..|..|.|    |....: :|.:|..::::...:|:|.::|.|:|.|||:::||
  Rat    19 LLILVAYLLQ-RNVNSGHM----PTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRI 78

  Fly    72 AR-------PGAKP-VLLVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVK 128
            .|       .|::| |||.|||...:|.||...|.:.||:.|...|:||||||.|||.:|:.|..
  Rat    79 PRGQTQLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKT 143

  Fly   129 LNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIH 193
            |:.:.|: :|:||:.|:..:||||:|:.:|||||.:|:.|.|:|||||..|:..|:.||...||.
  Rat   144 LSIDQDE-FWAFSYDEMARFDLPAVINFILQKTGQKKIYYVGYSQGTTMGFIAFSTMPELAHKIK 207

  Fly   194 LMSALAPVAFMKHMKAP----LMGIARMGMNMFGDNFELFP---HSEVFLNQCLSSAAMLKTCMR 251
            :..||||:|.:||.|:|    |:....|...:||....|:.   ..::|:..| ....:.:.|..
  Rat   208 MYFALAPIATVKHAKSPGTKFLLLPDMMIKGLFGRQEFLYQTRFFRQLFIYLC-GQMILDQICSN 271

  Fly   252 FYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESK-ENQRLYGRST 315
            ....:.|.|....||:...|.:.|.|.|.:::..||:.|...|.....:|:.|: :|:....:.|
  Rat   272 IILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNREKSNQPT 336

  Fly   316 PPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRKWNHMDMIWGISARRSIQP 380
            |..|::..:..|.|::.|..|:||..:||..|...:.|::.:....:|.|:|.|||:.|...:..
  Rat   337 PIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWGLDAPHRVYN 401

  Fly   381 RILQVMQ 387
            .|:.:|:
  Rat   402 EIIHLMK 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	22/61 (36%)
		Abhydrolase	73..239	CDD:304388	73/180 (41%)
		Abhydrolase_1	77..371	CDD:278959	105/302 (35%)
Lipm	XP_220066.4	Abhydro_lipase	49..111	CDD:282003	22/61 (36%)
		Abhydrolase_1	92..392	CDD:278959	105/301 (35%)
		Abhydrolase_5	93..>231	CDD:289465	65/138 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335529
Domainoid	1	1.000	229	1.000	Domainoid score	I2382
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H28267
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8975
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810