DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	389	Identity:	111/389 - (28%)
Similarity:	176/389 - (45%)	Gaps:	68/389 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 NTIQLLEKYKHPAETHQVTTDDKYILTLHRIARP-----GAKPVLLVHGLEDTSSTWIVMG-PES 99
            |..::.|.:.:..|.|.|.|.|.:||.||||..|     ..:.|...|||...|..|:.:. .|.
pombe    74 NIYEICEAFGYRVEEHLVRTQDNFILCLHRITHPKQSQHKREVVYCHHGLMTNSELWVAVNESER 138

  Fly   100 GLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQ 164
            .|.:.|..:|||||:||.|||:||:.|:...|. |:.:|:||..::.|:|:|..:|.:|::||.:
pombe   139 SLPFVLIESGYDVWLGNNRGNKYSRKHITYKPK-DEEFWNFSLDDMAMFDIPDTVDYILRETGRE 202

  Fly   165 KLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMKAPLMGIARMGMNMFGD----- 224
            ||:|.|.||||.......|..|:.|.|:::...|||....|...           |.|.|
pombe   203 KLNYIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPAYAPKGFS-----------NYFVDYIVKV 256

  Fly   225 NFELFPHSEVFLNQCLSSAAMLKTCMRFYWQ----------IVGK------NREEQNMTMFPVVL 273
            |.::..|  :|..:||..:..       :||          ||..      |.:..|:::...:.
pombe   257 NPKIMYH--LFGRRCLLPSVT-------FWQNICYPPIFVKIVDVSLKILFNWDLSNISLNQKLC 312

  Fly   274 G--HLPGGCNIKQALHYLQMQKSDRFCQYD--------YESKENQRLYGRSTPPDYRLERIKAPV 328
            |  ||....::|..:|:||:.|:..|..||        |.|:..|       .|.:....||.|:
pombe   313 GYAHLYSFSSVKSVVHWLQIIKNCTFQLYDDDMALLAGYGSRHYQ-------VPLFPTNNIKCPM 370

  Fly   329 ALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRKWNHMDMIWGISARRSIQPRILQVMQYWETG 392
            .:.:|..|.|..:| |.|.|  ||...:......:.|:|.:||...:..:.|.::..:::...|
pombe   371 LILWGGKDTLINME-VMRTA--LPPHAKEVSIAHYEHLDFLWGQDVKEEVFPVVIDALKHHSLG 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	19/58 (33%)
		Abhydrolase	73..239	CDD:304388	57/176 (32%)
		Abhydrolase_1	77..371	CDD:278959	93/325 (29%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	18/55 (33%)
		Abhydrolase_1	116..410	CDD:278959	93/324 (29%)
		Abhydrolase	<171..>242	CDD:304388	26/71 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	10	9.770