DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and SPBC14C8.15

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_595918.1	Gene:	SPBC14C8.15 / 2539842	PomBaseID:	SPBC14C8.15	Length:	460	Species:	Schizosaccharomyces pombe

Alignment Length:	383	Identity:	108/383 - (28%)
Similarity:	178/383 - (46%)	Gaps:	43/383 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRIARPG---------AKPVLLVHGLED 87
            |:.:.||. :||.|...:.:..|.|.|.|.|.|:|.|||:.:..         ..|||.:|||..
pombe    66 ANKLTDAR-DTIDLCALHGYDLEEHFVRTTDGYLLGLHRVYKKKKGKIEELNYLPPVLFIHGLMM 129

  Fly    88 TSSTWIV-MGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLP 151
            .|.:|:. :..|..:.:.|...|||||:||:|||:||..::|.:....| :|.||...|.::|:|
pombe   130 NSESWVCNLKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPK-FWDFSLDSIAIFDIP 193

  Fly   152 AMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAP-VAFMKH----MKAPL 211
            :::..:|....:..:|..|.|||....|...|...|....:....|||| :|..|:    :|:.:
pombe   194 SIVKYILSVNSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPAIAPKKYSGRTVKSII 258

  Fly   212 MGIARMGMNMFGDNFELFPHSEVFLNQCLSS---AAMLKTCMRFYWQIVGKNREEQNMTMFPVVL 273
            ...:::...|||.|..|  .|.||....|..   |.::...:||:....|||..|   |...|..
pombe   259 HANSQLLYLMFGRNSML--GSAVFWQAVLYPPVFAKIVDLFLRFFLSWTGKNISE---TQKIVAY 318

  Fly   274 GHLPGGCNIKQALHYLQMQKSDRFCQYD--------YESKENQRLYGRSTPPDYRLERIKAPVAL 330
            .||....::|..:|:.|:.:......||        |.:..|:  ..|     |.:|.|:.|:.|
pombe   319 SHLYSFTSVKCFVHWAQITRRKVLQMYDDSPGFKPSYYTNLNR--IAR-----YPIENIRLPITL 376

  Fly   331 YYGSNDYLSAVEDVHRLAKVLPNVVENHLYRKWNHMDMIWGISARRSIQPRILQVMQY 388
            .|||||.:   .|:..|...||.:.:......:.|:|:|.|.:.:..:..::::.:.:
pombe   377 VYGSNDNM---VDIETLKTQLPPLSQCIQIPNYEHLDIIMGDTKKDIVIQQVVEQLNH 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	21/63 (33%)
		Abhydrolase	73..239	CDD:304388	54/180 (30%)
		Abhydrolase_1	77..371	CDD:278959	91/310 (29%)
SPBC14C8.15	NP_595918.1	Abhydro_lipase	75..138	CDD:282003	21/62 (34%)
		Abhydrolase_1	119..412	CDD:278959	90/308 (29%)
		Abhydrolase_5	120..>260	CDD:289465	46/140 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	10	9.770