DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7329 and Lipo2

DIOPT Version :9

Sequence 1:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001309267.1	Gene:	Lipo2 / 101055671	MGIID:	3644466	Length:	398	Species:	Mus musculus

Alignment Length:	412	Identity:	132/412 - (32%)
Similarity:	211/412 - (51%)	Gaps:	51/412 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ICILVVLG-IYTLDGSGVLGGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTL 68
            :|::.||| |:.|.|.      .:|       .:||:|..::::.:.:|:|.::|.|||.|||.:
Mouse     8 MCLIQVLGKIFCLFGP------KKN-------PEAHMNVSEIIKHWDYPSEEYEVVTDDGYILPI 59

  Fly    69 HRIAR-------PGAKPVLLV-HGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKG 125
            :||..       |..|.|:.. |||..|...|:...|.:.|.:.|...|||||||:.||:.::|.
Mouse    60 NRIPHGKNNAKSPAPKMVVFCQHGLLATPGAWVSNPPVNSLAFILADAGYDVWMGSSRGSTWAKK 124

  Fly   126 HVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNA 190
            ||.|||:: |.:|.||:.::..|||||.|:.:|.|||.:::.|.||||||.......::..:...
Mouse   125 HVTLNPDS-KEFWDFSFDQMIKYDLPATINFILDKTGQKQIYYIGHSQGTLLAIGAFATNQKLAE 188

  Fly   191 KIHLMSALAPVAFMKHMKAPLMGIARMGMN--------MFGDNFELFP---HSEVFLNQCLSSAA 244
            ||.|...|||:..::|.|    ||:.:...        :||:. |..|   .|||  ..|:.:..
Mouse   189 KIKLNILLAPIYSVQHSK----GISHLASYLTPTTIKLLFGEK-EFLPTVVFSEV--GACVCNIN 246

  Fly   245 MLKT-CMRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESKE-N 307
            .... |......:.|.:.||.|.:...|.:.....|.::|..:||.|:.:|.....||:.|.. |
Mouse   247 FFTAICAAIMGSMGGYSPEELNKSRLDVYVKLNLAGTSVKVLIHYNQVGRSGILQAYDWGSPSLN 311

  Fly   308 QRLYGRSTPPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRK----WNHMDM 368
            .|.|.::|||.|.:|.:|.|.|::.|..|:||..|||    ::|...:.|..|.|    ::|.|.
Mouse   312 MRHYNQTTPPVYNVEDMKVPTAMFTGLKDFLSDPEDV----EILKPKIHNLTYLKTIPDFSHFDF 372

  Fly   369 IWGISARRSIQPRILQVMQYWE 390
            |||::.|..:...||.:::.::
Mouse   373 IWGLNTREEVSEEILTILRKYD 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	19/61 (31%)
		Abhydrolase	73..239	CDD:304388	64/184 (35%)
		Abhydrolase_1	77..371	CDD:278959	104/311 (33%)
Lipo2	NP_001309267.1	PLN02872	34..391	CDD:215470	121/368 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831873
Domainoid	1	1.000	227	1.000	Domainoid score	I2491
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I2905
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8736
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810