Protein Alignment Trim9 and TRIM55

DIOPT Version :9

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_908973.1
• Gene: TRIM55 / 84675
• HGNCID: 14215
• Length: 548
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 83/440 - (18%)
• Similarity: 135/440 - (30%)
• Gaps: 173/440 - (39%)

  Fly     1 MEDELRCPTCKQLYANP-VLLPCFHALCLGCALDI---QTPYSPGSALPGAVNGAGAASAAGHNG 61
            :|.:|.||.|.:::..| |:|||.|.||..||.||   ..||.|
Human    20 LEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLP--------------------- 63

  Fly    62 LHGNGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGV 126
            ..|....|.||.
Human    64 TRGGTTMASGGR----------------------------------------------------- 75

  Fly   127 VCCSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDR 191
                                             ..||.||..|..|..||..|.....:|.|:|
Human    76 ---------------------------------FRCPSCRHEVVLDRHGVYGLQRNLLVENIID- 106

  Fly   192 FCAREALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCG 256
                                 |.:|          |.|.|.:               :..:.:|.
Human   107 ---------------------IYKQ----------ESTRPEK---------------KSDQPMCE 125

  Fly   257 EH-EETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFI 320
            || ||.::.|||:|:.|.|.||.....|:...|..:....:.||:|||..:..|....
Human   126 EHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVGSN------- 183

  Fly   321 QRLKGMSDKVTESCMEFERLVHAQ----CEA---LIQAIHDRREYLLEAIRMDKDTKIRILKDQQ 378
            .|::|:..::.::|...|.....|    ||.   |...:.:|:..:.:.|...::.|:..::...
Human   184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVRALI 248

  Fly   379 SNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQE 428
            ...:..|:..:.|::..|:.:.|.:.|.|||....|:.:::.....:..|
Human   249 KKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9_like_C-I	2..37	CDD:319490	17/38 (45%)
		zf-B_box	250..291	CDD:306989	15/41 (37%)
		ClassIIa_HDAC_Gln-rich-N	298..420	CDD:330228	26/128 (20%)
		FN3	472..564	CDD:238020
		SPRY_PRY_TRIM67_9	561..735	CDD:293947
TRIM55	NP_908973.1	RING	26..85	CDD:238093	26/165 (16%)
		zf-B_box	119..161	CDD:279037	15/41 (37%)
		iSH2_PI3K_IA_R	168..294	CDD:304922	26/132 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	326..532

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910