Protein Alignment Trim9 and FSD1L

DIOPT Version :9

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_011517379.1
• Gene: FSD1L / 83856
• HGNCID: 13753
• Length: 547
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 126/574 - (21%)
• Similarity: 212/574 - (36%)
• Gaps: 163/574 - (28%)

  Fly   263 SQYCLS-----CKAPAC----GLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTE 318
            |:||..     ....||    .:.||.        :|||:    |:..|...:..|:.|......
Human    10 SKYCFKENENVTVDKACFLISNITIGP--------ESINL----QQEALQRIISTLANKNDEIQN 62

  Fly   319 FI----QRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQS 379
            ||    ..|||:.:..:....|.:.    :.::|...:.:.:|.::..|:.::..|.:.|:.|.|
Human    63 FIDTLHHTLKGVQENSSNILSELDE----EFDSLYSILDEVKESMINCIKQEQARKSQELQSQIS 123

  Fly   380 NCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNA-----APRVSP- 438
            .|...|:.:..|::|...:|...:...|.:....:.:|||         :.:|     .|:||.
Human   124 QCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVT---------MASAFRLSLKPKVSDN 179

  Fly   439 IVDLTLDDAALARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAENNSVTVAWQ-PPNHS 502
            :..|.:|.:...:.:..|.|:.:             |..|.|.|.:|...:|||||||: |...:
Human   180 MTHLMVDFSQERQMLQTLKFLPV-------------PKAPEIDPVECLVADNSVTVAWRMPEEDN 231

  Fly   503 FVEGYVLE--------------------LDDGSGGEFREVYCGKETICTVDGLHFNSMY-NARVK 546
            .::.::||                    :|:..|.|:           |:.||.|:|.| |.||:
Human   232 KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEY-----------TLSGLKFDSKYMNFRVR 285

  Fly   547 AFNSAGEGEYSELIGLQTAE--------------------VAWFTFDPVLSGGAGSGLIFSKNNA 591
            |.|.|..||||:.:.|:|..                    |.|   ||....|..|.:...:|..
Human   286 ACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEW---DPTGGKGQESKIKGKENKG 347

  Fly   592 TV--------------------------SVEGWEHR------VALGSVGFSRGVHYWEFTID--- 621
            :|                          :|.|...|      ..||......|.||||....
Human   348 SVHVTSLKKHTRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDC 412

  Fly   622 -NYTADTDPAFGVARIDVARNKMLGKDEKSFAMYIDRQRSWFQHN--SIHERRVEG-GITTGSTI 682
             :|:.      |||...:.:...|||...|:.::::   :|.|:.  :.|..:|:. .:|....|
Human   413 KSYSV------GVAYKTLGKFDQLGKTNTSWCIHVN---NWLQNTFAAKHNNKVKALDVTVPEKI 468

  Fly   683 GVLLDLERHTLSFLVNEMPQGSVAFRDLY-GVFYPAVSINRGVTLTMHTAMDAP 735
            ||..|.:...|||......|...:|:..: ....|...:..| .|::.|.|..|
Human   469 GVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCG-GLSLSTGMQVP 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9_like_C-I	2..37	CDD:319490
		zf-B_box	250..291	CDD:306989	7/36 (19%)
		ClassIIa_HDAC_Gln-rich-N	298..420	CDD:330228	25/125 (20%)
		FN3	472..564	CDD:238020	35/113 (31%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	47/233 (20%)
FSD1L	XP_011517379.1	iSH2_PI3K_IA_R	42..168	CDD:304922	26/138 (19%)
		FN3	203..303	CDD:238020	35/110 (32%)
		SPRY_PRY_FSD1	308..522	CDD:293958	46/227 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24099
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010