Protein Alignment Trim9 and btr33

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_017209516.1
• Gene: btr33 / 799840
• ZFINID: ZDB-GENE-090512-4
• Length: 586
• Species: Danio rerio
• Alignment Length: 685
• Identity: 139/685 - (20%)
• Similarity: 226/685 - (32%)
• Gaps: 249/685 - (36%)

  Fly     2 EDELRCPTCKQLYANPVLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHGNG 66
            |:..:|..|..::.:||.|||.|..|..|.|...|                   |:|
Zfish    45 EELFQCSVCLDVFTHPVSLPCGHTFCQSCVLAQWT-------------------ASG-------- 82

  Fly    67 GGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTG-----------SESVTSDQDQSDKVSIFS 120
                                 |||....|.....|.           :|.:...:.|:.|
Zfish    83 ---------------------SSHCPKCSAVFQETPDLCENSFAREMAEQIRKQKGQTQK----- 121

  Fly   121 EADSGVVCCSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAM 185
                       :||||.          ..||      :|..|||                 .:|.
Zfish   122 -----------SSRPVK----------AKVV------FCDMCPL-----------------EKAS 142

  Fly   186 EAIVDRFCAREALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQ 250
            .|:..         |.:|     |||         ||:| ...:|.:|  ..|||||:|:...::
Zfish   143 HAVKS---------CLVC-----VAS---------YCEA-HVTSHTSR--FTKHTLVQPQSMDKR 181

  Fly   251 RESVCGEHEETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSH---NLQQLSEK 312
               :|..||..|..||...::..|.||: ...|..|....:......:||:||.   :|:::..:
Zfish   182 ---ICRIHERPLELYCRYDQSAICVLCM-NAEHNTHHSVPVEREWMERKTQLSKTQTDLKRMIME 242

  Fly   313 ARSTTEFIQRLKGMSDKVTESCM--------EFERLVH-AQCEALIQAIHDRREYLLEAIRMDKD 368
            ..|..|.::....:|.:.||..|        ..::::. :|.|.|.:..|.::.......|:.|:
Zfish   243 RWSKVEDLRHSIKLSKENTEREMAHSVEVFTTLQQIIEKSQKELLRKMKHKQKSAEKHVERLIKE 307

  Fly   369 TKIRILKDQQSN-------------CTGKLQQTTGLIQFC-------------IEALKETDSAAF 407
            .::.|.|....|             |..:...|...:..|             :|.|:||.:||
Zfish   308 LEVEIAKLNTRNSELERLSSSEDHLCLIQAFPTLSEVPHCKSWSQISAHTCEGLELLRETLNAA- 371

  Fly   408 LQVGSMLINRVTNTDMTWHQEVTNAAPRVSP-IVDLTLD-DAA---LARAIDNLNFIQMRAVKDG 467
                    ..:..|.:  |.........:|. .|||||| |.|   ||.:.|.      ::|.||
Zfish   372 --------EELLKTQI--HSATKRELEAISQYAVDLTLDHDTANSWLAVSEDR------KSVSDG 420

  Fly   468 D---------ERCPAAPMTPTILPSDCSAENNS-------------VTVAWQPPNHSFVEGYV-L 509
            :         :|...|   |.||..:..:...|             :.||.:..|.   :|.| |
Zfish   421 NVERNFQNNTQRFDTA---PCILSKEPISRGRSYWEVGVSGKTAWDLGVARKSVNR---KGLVTL 479

  Fly   510 ELDDG-------SGGEFREVYCGKET-ICTVDGLH-----FNSMYNARVKAFNSAGEGEYSELIG 561
            ..:||       :|.|:|.  |.:|: :.::..|.     :....|.||..:::...|......|
Zfish   480 SPEDGYWAVCLRNGCEYRA--CNRESELLSLKSLPQTIGIYVDFENGRVSFYDTCACGHIYSFTG 542

  Fly   562 LQTAEVAWFTFDPVLSGGAGSGLIFSKNNATVSVE 596
            .:..|.....|:|.::.       ...|||.:.::
Zfish   543 QRFTESLLAYFNPDMND-------TGNNNAPLVIQ 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238	12/32 (38%)
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	15/44 (34%)
		Bbox2_TRIM9-like	255..291	CDD:380822	11/35 (31%)
		CC_brat-like	298..420	CDD:475168	29/159 (18%)
		FN3	472..564	CDD:238020	24/118 (20%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	7/36 (19%)
btr33	XP_017209516.1	RING_Ubox	43..111	CDD:473075	20/113 (18%)
		CCDC158	<103..>384	CDD:464943	73/370 (20%)
		Bbox_SF	133..175	CDD:469587	21/84 (25%)
		Bbox2_TRIM16-like	181..226	CDD:380827	11/48 (23%)
		SPRY_PRY_C-I_1	396..569	CDD:293968	44/193 (23%)