DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Trim9 and trim63

DIOPT Version :9

Sequence 1:NP_001188786.1 Gene:Trim9 / 34453 FlyBaseID:FBgn0051721 Length:740 Species:Drosophila melanogaster
Sequence 2:XP_012812733.1 Gene:trim63 / 780012 XenbaseID:XB-GENE-493173 Length:351 Species:Xenopus tropicalis


Alignment Length:460 Identity:84/460 - (18%)
Similarity:151/460 - (32%) Gaps:157/460 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEDELRCPTCKQLYANP-VLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHG 64
            :|.:|.||.|.:::..| |:|||.|.||..||.|:   :..|                       
 Frog    17 LEKQLICPICLEMFNKPVVILPCQHNLCRKCANDV---FQAG----------------------- 55

  Fly    65 NGGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCC 129
                          ||..            ||.||.:|..                         
 Frog    56 --------------NPYW------------STRSSVSGGR------------------------- 69

  Fly   130 SNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCA 194
                                          ..||.||..|..|..||..|.....:|.|:|    
 Frog    70 ------------------------------FRCPTCRHEVILDRHGVYGLQRNLLVENIID---- 100

  Fly   195 REALRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCGEHE 259
               :..|.|.:.|:                 ::..||                      :|.:||
 Frog   101 ---IYKQDCTSRPE-----------------KKENHP----------------------MCEKHE 123

  Fly   260 -ETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFIQRL 323
             |.::.|||||:...|.:|.....|:..||..:....::|||||:..:..|..........:.:|
 Frog   124 DEKINIYCLSCQVATCSMCKVFGVHKDCDVSPLQNVYQSQKTELNSCISMLVAGNDRIQCILSQL 188

  Fly   324 KGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKLQQT 388
            :.....:.|:....:..|....|.|.:.:.:::.:|::.|...::.|:..::........:||.:
 Frog   189 EESCKTIQENSQSKKESVKEMFETLFRNLEEKKTHLVQRISQAEEEKLNFVRSLIVRYQEQLQSS 253

  Fly   389 TGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDDAALARAI 453
            :.::|...:|:::...|.||.....||.::.........|.|:..  ...:...|||...:::.:
 Frog   254 SNVLQNAFQAMEQPGPANFLLESKQLIKKLMEASKGCQLEKTDHG--FENMDQFTLDMEHVSQCL 316

  Fly   454 DNLNF 458
            .:::|
 Frog   317 RSIDF 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Trim9NP_001188786.1 RING-HC_TRIM9_like_C-I 2..37 CDD:319490 16/35 (46%)
zf-B_box 250..291 CDD:306989 14/41 (34%)
ClassIIa_HDAC_Gln-rich-N 298..420 CDD:330228 23/121 (19%)
FN3 472..564 CDD:238020
SPRY_PRY_TRIM67_9 561..735 CDD:293947
trim63XP_012812733.1 RING 23..79 CDD:238093 26/162 (16%)
BBOX 117..156 CDD:197662 15/60 (25%)
iSH2_PI3K_IA_R 163..288 CDD:304922 23/124 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.