Protein Alignment Trim9 and Trim12a

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001355682.1
• Gene: Trim12a / 76681
• MGIID: 1923931
• Length: 327
• Species: Mus musculus
• Alignment Length: 232
• Identity: 48/232 - (20%)
• Similarity: 80/232 - (34%)
• Gaps: 43/232 - (18%)

  Fly   160 LTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCAREALRCQMCET--------DPKVASLICEQ 216
            :|||:|..|                |...|...|....  ||.|.|        |.||  .||..
Mouse    13 VTCPVCLNL----------------MVKPVSADCGHTF--CQGCITLYFESIKCDKKV--FICPV 57

  Fly   217 CEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCGEHEETLSQYCLSCKAPACGLCIGEL 281
            |.|.|..:...........:.:..:.||....:|:...|..|.:.|..:|.......|.||....
Mouse    58 CRISYQFSNLRPNRNVANIVERLKMFKPSPEEEQKVFNCARHGKKLQLFCRKDMMAICWLCERSQ 122

  Fly   282 RHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEF--------IQRLKGMSDKVTESCMEFE 338
            .|:.|....|....:..|.::..::|.:..:.:...:.        :|:|:...:.:..:..|.|
Mouse   123 EHRGHKTALIEEVAQEYKNQIQKDVQNVRSEFKRMRDIMDSEEKKELQKLRQEKEDILNNLAESE 187

  Fly   339 RLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILK 375
            . .|||...|::......|:.|:.      :.|.||:
Mouse   188 S-EHAQQSKLLEDFISDVEHQLQC------SDIEILQ 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	12/52 (23%)
		Bbox2_TRIM9-like	255..291	CDD:380822	9/35 (26%)
		CC_brat-like	298..420	CDD:475168	15/86 (17%)
		FN3	472..564	CDD:238020
		SPRY_PRY_TRIM67_9	561..735	CDD:293947
Trim12a	NP_001355682.1	RING_Ubox	8..78	CDD:473075	20/84 (24%)
		Bbox2_TRIM5-like	96..133	CDD:380819	9/36 (25%)
		EnvC	<130..>209	CDD:443969	12/79 (15%)