DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Trim9 and Rnf207

DIOPT Version :9

Sequence 1:NP_001188786.1 Gene:Trim9 / 34453 FlyBaseID:FBgn0051721 Length:740 Species:Drosophila melanogaster
Sequence 2:XP_001075996.1 Gene:Rnf207 / 691246 RGDID:1586262 Length:635 Species:Rattus norvegicus


Alignment Length:562 Identity:126/562 - (22%)
Similarity:182/562 - (32%) Gaps:178/562 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LRCPTCKQLYANPVLLPCFHALCLGCALDIQTPYSPGSALPG-AVNGAGAASAAGHNGLHGNGGG 68
            |.||.|...|.:|.||.|||..|.||             |.| |.:|..:.....|..|      
  Rat    23 LVCPLCHTQYEHPCLLDCFHDFCAGC-------------LRGRATDGRLSCPLCQHQTL------ 68

  Fly    69 AGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCCSNTS 133
                    |..|:|                           ...:|::..|.             
  Rat    69 --------VKGPSG---------------------------LPPADRLLQFL------------- 85

  Fly   134 RPVSYAGTGLLPGVGNVVAPPGAAYCLTCPL-CRKLVFFDDGGVRNLPTYRAMEAIVDRFCAREA 197
              |..:|.|:           .|.:|..|.| |.|                              
  Rat    86 --VDSSGDGI-----------EAVHCANCDLECSK------------------------------ 107

  Fly   198 LRCQMCETDPKVASLICEQCEIRYCDACRELTHPARGPLAKHTLVKPRGAAQQRE----SVCGEH 258
               |..||     :..|..|....|..|||.||.|| ..|:|.:|    |..||.    ..|..|
  Rat   108 ---QDAET-----TYFCNTCGQPLCARCREETHRAR-MFARHDIV----ALGQRSRDFIQKCKLH 159

  Fly   259 EETLSQYCLSCKAPACGLCI----GELRHQAHDVQSINVT-CKAQKTELSHNLQQ--LSEKA--R 314
            .|....:....|:..|..|.    ||.|....|::|..|. |:        .|:|  |:.||  .
  Rat   160 SEPYIVFSTDKKSLLCIRCFRDMQGESRAHCVDLESAYVQGCE--------RLEQAVLAVKALQT 216

  Fly   315 STTEFIQRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQS 379
            :|.|.|..|:.|.::|..|..|.|..:||...::...:.:|:..||:.::...:.|.:..|:|.:
  Rat   217 ATKEAIALLQAMVEEVRHSAAEEEAAIHALFGSMQDRLAERKALLLQTVQSQYEEKDKAFKEQLT 281

  Fly   380 NCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTL 444
            :....|......:..|...|.....|.||.:|..|:.|:        |.:.....|:.|.....:
  Rat   282 HLASLLPTLQVHLVICSSFLSLASKAEFLDLGYELMERL--------QGIVTRPHRLRPAQSSKI 338

  Fly   445 DD---AALARAIDNLNFI-QMRAVKD-GDERCPAAPMTPTIL-----PSDCSAENNSVTVAWQPP 499
            ..   |..||.::.|..: ..|||.. |.....|...:|.:|     ||.....:.|  ...:|.
  Rat   339 ASDHRAEFARCLEPLLLLGPRRAVSTVGGANTLAGGSSPKVLKTQSCPSPVGKMSGS--PVQKPS 401

  Fly   500 NHSFVEGYVLELDDGSGGEFREVYCGKETICTVDGLHFNSMY 541
            .|.|:...|| |.:|....|.| :|          .|:...|
  Rat   402 PHRFISTKVL-LAEGEDTPFTE-HC----------RHYEDSY 431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Trim9NP_001188786.1 RING-HC_TRIM9_like_C-I 2..37 CDD:319490 14/31 (45%)
zf-B_box 250..291 CDD:306989 12/48 (25%)
ClassIIa_HDAC_Gln-rich-N 298..420 CDD:330228 31/125 (25%)
FN3 472..564 CDD:238020 18/75 (24%)
SPRY_PRY_TRIM67_9 561..735 CDD:293947
Rnf207XP_001075996.1 RING 25..65 CDD:238093 17/52 (33%)
zf-B_box 100..145 CDD:279037 20/87 (23%)
iSH2_PI3K_IA_R 202..321 CDD:304922 31/134 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4367
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.