Protein Alignment Trim9 and trim8

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001027512.1
• Gene: trim8 / 613104
• XenbaseID: XB-GENE-1006787
• Length: 551
• Species: Xenopus tropicalis
• Alignment Length: 699
• Identity: 140/699 - (20%)
• Similarity: 212/699 - (30%)
• Gaps: 259/699 - (37%)

  Fly     2 EDELRCPTCKQLYANPVLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHGNG 66
            |:||.||.|..::..||.|||.|..|.||
 Frog    10 EEELICPICLHVFIEPVQLPCKHNFCRGC------------------------------------ 38

  Fly    67 GGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEA---DSGVVC 128
                                                                .|||   ::|:|
 Frog    39 ----------------------------------------------------ISEAWAKETGMV- 50

  Fly   129 CSNTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYR---AMEAIVD 190
                                            .||.|.:       .....||..   .:..||:
 Frog    51 --------------------------------RCPECNQ-------AYNQKPTLEKNLKLTNIVE 76

  Fly   191 RF------CAREALRCQMCETDPKV-ASLICEQCEIRYCDACRELTH-----PARGPLAKHTLVK 243
            :|      .|...|.|..|...|.: |..||.:||...|.: ...||     .|||    |.||:
 Frog    77 KFNSLNVDKAPSILHCVFCRRGPPLPAQKICLRCEAPCCQS-HVQTHLQQPSTARG----HLLVE 136

  Fly   244 PRGAAQQRESVCGEHEETLSQYCLSCKAPACGLCI---GELRHQAHDVQSINVTCKAQKTELSHN 305
               |...|...|.:|......:|.:.:...|..|.   |  .||.|.|..:.:.....:..|...
 Frog   137 ---AEDVRAWSCPQHNAYRLYHCEAEQVAVCQFCCYYSG--AHQGHSVCDVEIRRNEIRKMLIKQ 196

  Fly   306 LQQLSEKARSTTEFIQRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLEAIRMDKDTK 370
            ..:|.|:.:...:.:.:|:  |||         |||..:...|...:..:.:.|.:.:..|....
 Frog   197 QDRLEEREQDIEDQLYKLE--SDK---------RLVEEKVSQLKDEVRQQYDKLHQILDEDLRKT 250

  Fly   371 IRIL-KDQQSNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLINRVTNT-------DMTWHQ 427
            :.|| |.|...|.....|...|.:...||.|...|...:...:..||.:.||       |.|  |
 Frog   251 MDILDKAQAKFCNENAAQVLQLNERMQEAKKLLSSVQVMFDKTEDINFMKNTKSVKILMDRT--Q 313

  Fly   428 EVTNAA---PRVSPI-VDLTLDDAALARAIDNLNFIQMRAVKDGDERCPAAPMTPTILPSDCSAE 488
            ..|..:   |::..: ..|.|.:.|....       |:|.:.:|....| .|...:|....||..
 Frog   314 NCTGGSLPPPKIGHLNSKLFLSEIAKKEK-------QLRKMLEGPFNTP-VPFLQSIPMYSCSVS 370

  Fly   489 NNSVTVAWQPPNHS--FVEGYVLELDDGSGGEFREVYCGKETICTVDGLHFNSMYNARVKAFNSA 551
            ::..    :...||  |.||..  ||..||              ||.|.:        :...:|:
 Frog   371 SSGA----EKRKHSAAFPEGNF--LDPASG--------------TVSGQY--------ISQGSSS 407

  Fly   552 GEGEYSE----------LIGLQTAEVAWFT---FDP------------VLSG-GAGSGLIFSKNN 590
            |||:.::          ::||.:......:   |:|            |||. |....|:.|.:|
 Frog   408 GEGQSAQPMVPCSSTQHIVGLPSGPQPVHSNSVFNPSHYPNSTSSQQSVLSQYGGRKILVCSVDN 472

  Fly   591 ---ATVSVEGWEHRVALGSVGFSRGVHY-WEFTIDNYTADTDPAFGVAR 635
               ::||    .|.   |...:.|..|: |..:...|:....|...|.:
 Frog   473 CYCSSVS----NHS---GHQPYPRSGHFPWTVSSQEYSHPLPPTPSVTQ 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238	15/32 (47%)
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	17/50 (34%)
		Bbox2_TRIM9-like	255..291	CDD:380822	10/38 (26%)
		CC_brat-like	298..420	CDD:475168	26/122 (21%)
		FN3	472..564	CDD:238020	23/103 (22%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	21/95 (22%)
trim8	NP_001027512.1	RING-HC_TRIM8_C-V	2..68	CDD:438242	25/185 (14%)
		Bbox1_TRIM8_C-V	90..137	CDD:380896	18/54 (33%)
		Bbox2_TRIM8_C-V	142..183	CDD:380821	10/42 (24%)
		PRK12704	181..>280	CDD:237177	21/109 (19%)