DRSC/TRiP Functional Genomics Resources

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Protein Alignment Trim9 and Trim3

DIOPT Version :9

Sequence 1:NP_001188786.1 Gene:Trim9 / 34453 FlyBaseID:FBgn0051721 Length:740 Species:Drosophila melanogaster
Sequence 2:NP_001347354.1 Gene:Trim3 / 55992 MGIID:1860040 Length:750 Species:Mus musculus


Alignment Length:311 Identity:65/311 - (20%)
Similarity:114/311 - (36%) Gaps:51/311 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   154 PGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRFCAREALRCQMCETDPKVASLICEQCE 218
            |..:..|:||:||:.....:.||         .|:.:.|.               ::||:     
Mouse    51 PPQSLTLSCPVCRQTSILPEQGV---------SALQNNFF---------------ISSLM----- 86

  Fly   219 IRYCDACRELTHPARGPLAKHTLVKPRGAAQQRESVCGEHE-------ETLSQYCLSCKAPACGL 276
                :|.::....|..|...|    |..|...|...|..||       :|:..||.:|:...||.
Mouse    87 ----EAMQQAPEGAHDPEDPH----PLSAVAGRPLSCPNHEGKEPLYHQTMEFYCEACETAMCGE 143

  Fly   277 C-IGELRHQAHDVQSINVTCKAQKTELSHNLQQLSEKARSTTEFIQRLKGMSDKVTESCMEFERL 340
            | .||  |:.|....:....:..|..|...|:.:..:....:..|..:.|:|.::.|...|....
Mouse   144 CRAGE--HREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQ 206

  Fly   341 VHAQCEALIQAIHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKLQQTTGLIQFCIEALKETDSA 405
            :.|..|.|.||:..|::.|:..:......|.::|:.|........:.......|..:||:...:.
Mouse   207 ISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAP 271

  Fly   406 AFLQVGSMLINRVTNTDMTWHQEVTNAAPRVSPIVDLTLDDAALARAIDNL 456
            ..|.|...:..|:.........|    .|..:..::|.|:...|.|::.||
Mouse   272 EVLLVRKHMRERLAALAAQAFPE----RPHENAQLELVLEVDGLRRSVLNL 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Trim9NP_001188786.1 RING-HC_TRIM9_like_C-I 2..37 CDD:319490
zf-B_box 250..291 CDD:306989 15/48 (31%)
ClassIIa_HDAC_Gln-rich-N 298..420 CDD:330228 24/121 (20%)
FN3 472..564 CDD:238020
SPRY_PRY_TRIM67_9 561..735 CDD:293947
Trim3NP_001347354.1 RING-HC_TRIM3 19..63 CDD:319682 4/11 (36%)
RING-HC finger (C3HC4-type) 22..62 CDD:319682 4/10 (40%)
Bbox_SF 107..159 CDD:381767 16/53 (30%)
BBC 164..290 CDD:128778 24/125 (19%)
Filamin 323..424
IG_FLMN 328..425 CDD:214720
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..470
NHL_TRIM2_like 477..750 CDD:271330
NHL 1 479..522
NHL repeat 495..534 CDD:271330
NHL 2 526..569
NHL repeat 542..581 CDD:271330
NHL 3 570..611
NHL repeat 584..621 CDD:271330
NHL 4 615..658
NHL repeat 628..669 CDD:271330
NHL 5 662..705
NHL repeat 675..717 CDD:271330
NHL 6 706..749
NHL repeat 720..746 CDD:271330
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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