DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trim9 and si:ch211-12p12.2

DIOPT Version :9

Sequence 1:	NP_001188786.1	Gene:	Trim9 / 34453	FlyBaseID:	FBgn0051721	Length:	740	Species:	Drosophila melanogaster
Sequence 2:	XP_001920571.1	Gene:	si:ch211-12p12.2 / 558611	ZFINID:	ZDB-GENE-131125-5	Length:	453	Species:	Danio rerio

Alignment Length:	409	Identity:	93/409 - (22%)
Similarity:	155/409 - (37%)	Gaps:	89/409 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 AREALRCQMCE---TDPKVASL---ICEQC--------EIRYCDACRELT---HPARGPLAKH-- 239
            :.|...|.||.   .||.|.|.   .|::|        :.:.|..||..:   .|....:.|:
Zfish     5 SEEDFSCPMCHDIFKDPVVLSCSHSFCKECLQQFWKTKKTQECPVCRRRSSKDFPPCNLVLKNLC 69

  Fly   240 -TLVKPRGAAQQRESVCGEHEETLSQYCLSCKAPACGLCIGELRHQAHDVQSINVTCKAQKTELS 303
             :.:|.|......|.:|..|.|.|..:||..|...|.:|:...:|..|..:.|.....:.|.:|:
Zfish    70 ESFLKERKYGCSSEEICSLHGEKLKLFCLEDKQLMCVVCVTSKQHDNHKFRPIGEVVSSHKKDLN 134

  Fly   304 HNLQQLSEKARSTTEF-------IQRLKGMSDKVTESCMEFERLVHAQCEALIQAIHDRREYLLE 361
            ..|:.|.||.:...:.       ||.:|..:|       :.|..:..|.|.|.|.:.|..|..:.
Zfish   135 TALKSLQEKIKHNKDIKEEFEKTIQHIKTQAD-------DTEHQIKQQFEKLHQFLRDEEEATIT 192

  Fly   362 AIRMDKDTKIRILKDQQSNCTGKLQQTTGLIQFCIEALKETDSAAFLQ--VGSMLINRVTNTDMT 424
            |:|.:::.|.:::|::.......:...:..|:...|.|| .:...||:  .|||...:::..|
Zfish   193 ALREEEEQKRQVMKEKLEEMNTHISALSCTIRDTEEMLK-ANGVCFLKEFPGSMKRVQISQPD-- 254

  Fly   425 WHQEVTNAAPRVSPIVDLTLDDAALARAIDNLNFIQMRAVKDGDERCPAA--PMTPT---ILPSD 484
             .|..:.|...||             :.:.||.:...|.::|.....|..  |.|..   ||..|
Zfish   255 -PQTPSGALINVS-------------QYLGNLQYRVWRKMQDIVHYTPVILDPNTANPHLILSDD 305

  Fly   485 CSAENNSVTVAWQPPNHSFVEGYVLELDDGSGGEFREVYCGKETICTVDGLHFNS---MYNARVK 546
            .::...:......|||....:.|...|  ||.|                   |||   .::..||
Zfish   306 LTSGRGTGNRQPLPPNPERFDWYFCVL--GSEG-------------------FNSGKHSWDVEVK 349

  Fly   547 AFNSAGEGEYSELIGLQTA 565
              :::|.|     :|:.||
Zfish   350 --DNSGWG-----LGVTTA 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9_like_C-I	2..37	CDD:319490
		zf-B_box	250..291	CDD:306989	12/40 (30%)
		ClassIIa_HDAC_Gln-rich-N	298..420	CDD:330228	30/130 (23%)
		FN3	472..564	CDD:238020	22/99 (22%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	3/5 (60%)
si:ch211-12p12.2	XP_001920571.1	RING	11..52	CDD:238093	11/40 (28%)
		zf-B_box	81..122	CDD:279037	12/40 (30%)
		DUF4200	130..>219	CDD:290574	21/95 (22%)
		SPRY	288..449	CDD:295394	24/102 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910