Protein Alignment Trim9 and mid1

DIOPT Version :10

• Sequence 1: NP_001188786.1
• Gene: Trim9 / 34453
• FlyBaseID: FBgn0051721
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001006876.1
• Gene: mid1 / 448651
• XenbaseID: XB-GENE-494584
• Length: 668
• Species: Xenopus tropicalis
• Alignment Length: 775
• Identity: 182/775 - (23%)
• Similarity: 286/775 - (36%)
• Gaps: 240/775 - (30%)

  Fly     1 MEDELRCPTCKQLYANPVLLPCFHALCLGCALDIQTPYSPGSALPGAVNGAGAASAAGHNGLHGN 65
            :|.||.||.|.:|:.:|:||||.|:||..||
 Frog     4 LESELTCPICLELFEDPLLLPCAHSLCFNCA---------------------------------- 34

  Fly    66 GGGAGGGAAAPVTNPNGPGTRHSSHSSAASTASSNTGSESVTSDQDQSDKVSIFSEADSGVVCCS 130
                                    |....|..::|...||:.:.|
 Frog    35 ------------------------HRILVSHCANNESVESINAFQ-------------------- 55

  Fly   131 NTSRPVSYAGTGLLPGVGNVVAPPGAAYCLTCPLCRKLVFFDDGGVRNLPTYRAMEAIVDRF--- 192
                                           ||.||.::.....|:..|.....::.|:|||
 Frog    56 -------------------------------CPTCRYVITLSKRGLEGLKRNVTLQNIIDRFQKA 89

  Fly   193 -----------------------CAREALRCQMCETD-PKVASLICEQCEIRYCDACRELTHPAR 233
                                   .:.|.:.||.|:.| .:.|...|..||:.||:.|.:.|||.:
 Frog    90 SVSGPNSPSETRRERAYDTTNSMTSSEKVLCQFCDQDQAREAVKTCVTCEVSYCEDCLKATHPNK 154

  Fly   234 GPLAKHTLVKPRGAAQQRESVCGEHE-ETLSQYCLSCKAPACGLC--IGELRHQAHDVQSINVTC 295
            .|...|.|::|...:..|..:|.||| |.::.||::.....|.||  :|  ||:.|.|.::....
 Frog   155 KPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVG--RHRDHQVAALGDRY 217

  Fly   296 KAQKTELSHNLQQLSEKARSTTEFIQRLKGMSDKVTESCMEFERLVHA---------QCEALIQA 351
            ...|..|..||..|.::   .||    ::.:..|:.::|.:.|  |:|         :.:.||:.
 Frog   218 DKLKQSLESNLTNLIKR---NTE----MEILLSKLIQTCQQVE--VNASRQEAKLMEESDQLIEI 273

  Fly   352 IHDRREYLLEAIRMDKDTKIRILKDQQSNCTGKLQQTTGLIQFCIEALKETDSAAFLQVGSMLIN 416
            |..||:.:...|:..|..::|.|..|.:||...::::|.||....::|||.|.|.|||....:..
 Frog   274 IQQRRQIIGTKIKEGKVVRLRKLAQQVANCKQCIERSTSLISQAEQSLKENDHARFLQSAKNITE 338

  Fly   417 RVTNTDMTWHQEVTNAAPRVSPIVDL--TLDDAAL-----ARAIDNLNFIQMRAVKDGDERCPAA 474
            ||:        ..|.::..:.|.::|  |.|..||     .:.::.|:::             .|
 Frog   339 RVS--------MATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYL-------------TA 382

  Fly   475 PMTPTILPSDCSAENNSVTVAWQPPNHSFVEGYVLELDDGSGGEFREVYCG-----------KET 528
            |..|.|....|:|..:::||.|...:...|..|.|:....:|.......|.           |:.
 Frog   383 PNPPVIREELCTASYDTITVHWTSEDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQN 447

  Fly   529 ICTVDGLHFNSMYNARVKAFNSAGEGEYSELIGLQTAEVAWFTFDPVLSGGAGSGLIFSKNNATV 593
            ..||.||...:.|...|||.|.|| ...||...|:|.... |..||   ..|...|..|.:|.||
 Frog   448 HYTVHGLQSGTKYIFIVKAINQAG-SRNSEPGKLKTNSQP-FKLDP---KSAHRKLKVSHDNLTV 507

  Fly   594 SVEGWEHRVA--------------LGSVGFSRGVHYWEFTIDNYTADTDPAFGVARIDVARNKML 644
            ..:....:.:              .|:|....|.||||..|   :..|..|.|:|.....:::.:
 Frog   508 ERDETSSKKSHTPERFTSQGSYGVAGNVFLDSGRHYWEVVI---SGSTWYAIGIAYKSAPKHEWI 569

  Fly   645 GKDEKSFAMYIDRQRSW-FQHN--------SIHERRVEGGITTGSTIGVLLDLERHTLSF 695
            ||:..|: ::.....:| .:||        |.|.|||          |:|||.:..:|||
 Frog   570 GKNTASW-VFCRCNNNWAVRHNSKEIPIEPSPHLRRV----------GILLDYDNGSLSF 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trim9	NP_001188786.1	RING-HC_TRIM9-like_C-I	2..>35	CDD:438238	17/32 (53%)
		Bbox1_TRIM9-like_C-I	199..244	CDD:380861	17/45 (38%)
		Bbox2_TRIM9-like	255..291	CDD:380822	15/38 (39%)
		CC_brat-like	298..420	CDD:475168	37/130 (28%)
		FN3	472..564	CDD:238020	29/102 (28%)
		SPRY_PRY_TRIM67_9	561..735	CDD:293947	41/158 (26%)
mid1	NP_001006876.1	RING-HC_MID1	3..74	CDD:438411	28/178 (16%)
		Bbox1_MID1_C-I	116..165	CDD:380894	18/48 (38%)
		Bbox2_MID1_C-I	169..215	CDD:380880	16/47 (34%)
		CC_brat-like	220..345	CDD:475168	37/141 (26%)
		COS	324..375	CDD:465805	14/58 (24%)
		FN3	396..482	CDD:238020	23/86 (27%)
		SPRY_PRY_TRIM18	486..662	CDD:240472	39/151 (26%)